Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.67 |
| ▸ | SNCA | P37840 | 1/20 | 0.64 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.64 |
| ▸ | MAOB | P27338 | 3/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.60 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.59 |
| ▸ | P4HB | P07237 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4620101 | 0.92 | ABCG2 (0.74) | SNCAABCG2MAOBMAOANR1H4 | |
| SCHEMBL4620096 | 0.92 | ABCG2 (0.74) | SNCAABCG2MAOBMAOANR1H4 | |
| SCHEMBL30428796 | 0.92 | ABCG2 (0.74) | SNCAABCG2MAOBMAOANR1H4 | |
| SCHEMBL28906385 | 0.87 | DPP4 (0.61) | DPP4SNCAABCG2MAOBNR1H4 | |
| SCHEMBL5598882 | 0.84 | TNFRSF1A (0.79) | ABCG2TNFRSF1AMAPTABCB1P4HB | |
| SCHEMBL5598880 | 0.84 | TNFRSF1A (0.79) | ABCG2TNFRSF1AMAPTABCB1P4HB | |
| SCHEMBL32681387 | 0.84 | TNFRSF1A (0.79) | ABCG2TNFRSF1AMAPTABCB1P4HB | |
| SCHEMBL5599587 | 0.84 | PTPN1 (0.57) | DPP4ABCG2MAOBMAOANR1H4 | |
| SCHEMBL9852303 | 0.81 | MAOB (0.74) | DPP4MAOBMAOATNFRSF1AMAPT | |
| SCHEMBL5598901 | 0.81 | CXCL12 (0.82) | ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764363-A2 | SUBSTITUTED ACETOPHENONEDERIVATIVES | Riemser Arzneimittel AG (DE) | 2007-03-21 | — | — | EP | claimed |
| EP-1764363-A2 | SUBSTITUTED ACETOPHENONEDERIVATIVES | Riemser Arzneimittel AG (DE) | 2007-03-21 | — | — | EP | disclosed |
| EP-1764363-A2 | SUBSTITUTED ACETOPHENONEDERIVATIVES | Riemser Arzneimittel AG (DE) | 2007-03-21 | — | — | EP | disclosed |