Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 3/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.39 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7032426 | 0.89 | CYP19A1 (0.51) | ALDH1A1CYP19A1NPSR1CYP3A4ESR1 | |
| SCHEMBL8611247 | 0.89 | CYP19A1 (0.51) | ALDH1A1CYP19A1NPSR1CYP3A4ESR1 | |
| SCHEMBL10893461 | 0.87 | ALDH1A1 (0.41) | GAAALDH1A1CYP19A1NPSR1KMT2A | |
| SCHEMBL11266486 | 0.87 | ALDH1A1 (0.44) | GAAALDH1A1CYP19A1NPSR1KMT2A | |
| SCHEMBL7561836 | 0.85 | GAA (0.48) | GAAALDH1A1RECQLCYP19A1NR1I2 | |
| SCHEMBL7721313 | 0.85 | GAA (0.48) | GAAALDH1A1RECQLCYP19A1NR1I2 | |
| SCHEMBL13506110 | 0.85 | GAA (0.48) | GAAALDH1A1RECQLCYP19A1NR1I2 | |
| SCHEMBL2710225 | 0.85 | CYP2D6 (0.55) | ALDH1A1NR1I2NPSR1KMT2ACYP3A4 | |
| SCHEMBL7929087 | 0.85 | CYP2D6 (0.55) | ALDH1A1NR1I2NPSR1KMT2ACYP3A4 | |
| SCHEMBL8732737 | 0.85 | CYP2D6 (0.55) | ALDH1A1NR1I2NPSR1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1889639-A2 | Methods and compositions containing succinimide or maleimide derivatives of antineoplastic agents, for producing long lasting antineoplastic agents | ConjuChem Biotechnologies Inc. (CA) | 2008-02-20 | — | — | EP | disclosed |
| EP-1212120-A2 | METHODS AND COMPOSITIONS CONTAINING SUCCINIMIDE OR MALEIMIDE DERIVATIVES OF ANTINEOPLASTIC AGENTS, FOR PRODUCING LONG LASTING ANTINEOPLASTIC AGENTS | Conjuchem, Inc. (CA) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001017614-A2 | METHODS AND COMPOSITIONS CONTAINING SUCCINIMIDE OR MALEIMIDE DERIVATIVES OF ANTINEOPLASTIC AGENTS | CONJUCHEM, INC. (CA) | 2001-03-15 | — | — | WO | disclosed |