Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 3/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13506110 | 1.00 | GAA (0.48) | GAAALDH1A1RECQLCYP19A1NPSR1 | |
| SCHEMBL7561836 | 1.00 | GAA (0.48) | GAAALDH1A1RECQLCYP19A1NPSR1 | |
| SCHEMBL7948711 | 0.85 | HTR1B (0.49) | ALDH1A1CYP19A1NPSR1ESR1KMT2A | |
| SCHEMBL4620169 | 0.85 | GAA (0.51) | GAAALDH1A1RECQLCYP19A1NPSR1 | |
| SCHEMBL11209066 | 0.83 | ESR1 (0.54) | ALDH1A1NPSR1ESR1ESR2LTA4H | |
| SCHEMBL19639015 | 0.79 | CNR1 (0.40) | ALDH1A1CYP19A1ESR1ESR2KMT2A | |
| SCHEMBL10893461 | 0.78 | ALDH1A1 (0.41) | GAAALDH1A1CYP19A1NPSR1ESR1 | |
| SCHEMBL9859772 | 0.76 | CYP2D6 (0.52) | ALDH1A1NPSR1NR1I2ESR1ESR2 | |
| SCHEMBL11212723 | 0.75 | LMNA (0.47) | GAALTA4HLMNA | |
| SCHEMBL8611247 | 0.74 | CYP19A1 (0.51) | ALDH1A1CYP19A1NPSR1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104788300-B | Ospemifene polymorphic substance | 南京华威医药科技开发有限公司 | 2017-01-11 | — | — | CN | disclosed |
| CN-104788300-A | Ospemifene polymorphic substance | NANJING HUAWE MEDICAL TECHNOLOGY DEV CO LTD | 2015-07-22 | — | — | CN | disclosed |
| US-6395785-B1 | ANTICHOLESTEROL AGENTS; HORMONE REPLACEMENT THERAPY | ORION CORPORATION (FI) | 2002-05-28 | — | — | US | disclosed |