Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | ADH4 | P08319 | 1/20 | 0.39 |
| ▸ | ADH7 | P40394 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4619210 | 1.00 | LTA4H (0.47) | LTA4HCYP2D6EPHX1CA12CA1 | |
| SCHEMBL4620202 | 1.00 | LTA4H (0.47) | LTA4HCYP2D6EPHX1CA12CA1 | |
| SCHEMBL22413014 | 0.98 | LTA4H (0.44) | LTA4HCYP2D6EPHX1CA12CA1 | |
| SCHEMBL22413011 | 0.98 | LTA4H (0.44) | LTA4HCYP2D6EPHX1CA12CA1 | |
| SCHEMBL5592373 | 0.94 | LTA4H (0.41) | LTA4HCYP2D6EPHX1CA12CA1 | |
| SCHEMBL5592372 | 0.94 | LTA4H (0.41) | LTA4HCYP2D6EPHX1CA12CA1 | |
| SCHEMBL1377279 | 0.90 | SIGMAR1 (0.42) | LTA4HKMT2A | |
| SCHEMBL1377280 | 0.90 | SIGMAR1 (0.42) | LTA4HKMT2A | |
| SCHEMBL4620611 | 0.81 | BCHE (0.46) | LTA4HEPHX1KMT2AMEN1NPC1 | |
| SCHEMBL20422606 | 0.81 | EPHX1 (0.42) | LTA4HCYP2D6EPHX1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111836632-A | BCL9 peptides and variants thereof | 温特瑞克斯制药有限公司 | 2020-10-27 | — | — | CN | disclosed |
| EP-1884230-A1 | PARAKERATOSIS INHIBITOR, PORE-SHRINKING AGENT OR AGENT FOR PREVENTING/AMELIORATING ROUGH SKIN AND EXTERNAL COMPOSITION FOR SKIN | Shiseido Company, Limited (JP) | 2008-02-06 | — | — | EP | disclosed |
| US-20070142287-A1 | Compositions And Methods For Treatment Of Cancer | BIOMED SOLUTIONS, LLC (US) | 2007-06-21 | — | — | US | disclosed |
| US-20060057729-A1 | Diffraction grating-based encoded element having a substance disposed thereon | ILLUMINA, INC. | 2006-03-16 | — | — | US | disclosed |
| US-5128448-A | Peptide hormones | HOFFMAN-LA ROCHE INC. (US) | 1992-07-07 | — | — | US | disclosed |