Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.37 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH4 | P08319 | 1/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5592372 | 1.00 | LTA4H (0.41) | LTA4HCYP2D6EPHX1ADH1BADH1C | |
| SCHEMBL22413011 | 0.96 | LTA4H (0.44) | LTA4HCYP2D6EPHX1ADH1BADH1C | |
| SCHEMBL22413014 | 0.96 | LTA4H (0.44) | LTA4HCYP2D6EPHX1ADH1BADH1C | |
| SCHEMBL4620202 | 0.94 | LTA4H (0.47) | LTA4HCYP2D6EPHX1ADH1BADH1C | |
| SCHEMBL4620196 | 0.94 | LTA4H (0.47) | LTA4HCYP2D6EPHX1ADH1BADH1C | |
| SCHEMBL4619210 | 0.94 | LTA4H (0.47) | LTA4HCYP2D6EPHX1ADH1BADH1C | |
| SCHEMBL1377279 | 0.92 | SIGMAR1 (0.42) | LTA4HSIGMAR1MMEACECPA1 | |
| SCHEMBL1377280 | 0.92 | SIGMAR1 (0.42) | LTA4HSIGMAR1MMEACECPA1 | |
| SCHEMBL31654141 | 0.83 | PIK3CD (0.37) | LTA4HSIGMAR1MMEACECPA1 | |
| SCHEMBL23080195 | 0.81 | ADH1B (0.38) | CYP2D6EPHX1ADH1BADH1CADH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007006714-A1 | CYSTEINE PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2007-01-18 | — | — | WO | disclosed |