Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6695121 | 0.81 | LMNA (0.43) | ADAMTS5MMP2LMNA | |
| SCHEMBL23354127 | 0.79 | ADAMTS5 (0.35) | ADAMTS5MMP2LMNA | |
| SCHEMBL6695577 | 0.78 | ADAMTS5 (0.40) | ADAMTS5MMP2LMNA | |
| SCHEMBL23354392 | 0.71 | ADAMTS5 (0.32) | ADAMTS5MMP2 | |
| SCHEMBL4620067 | 0.68 | TSHR (0.34) | — | |
| SCHEMBL1132700 | 0.67 | SMN1; SMN2 (0.42) | ADAMTS5MMP2LMNA | |
| SCHEMBL13209009 | 0.67 | SMN1; SMN2 (0.42) | ADAMTS5MMP2LMNA | |
| SCHEMBL4620116 | 0.67 | LMNA (0.31) | LMNA | |
| SCHEMBL17738394 | 0.66 | LMNA (0.36) | LMNA | |
| SCHEMBL4620211 | 0.66 | POLB (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1883454-A2 | AGENT FOR PERMANENT HAIR WAVING CONTAINING HETEROCYCLIC MERCAPTO COMPOUND | Showa Denko K.K. (JP) | 2008-02-06 | — | — | EP | disclosed |
| WO-2006126729-A2 | AGENT FOR PERMANENT HAIR WAVING CONTAINING HETEROCYCLIC MERCAPTO COMPOUND | SHOWA DENKO K.K. (JP) | 2006-11-30 | — | — | WO | disclosed |