SCHEMBL4620067

SCHEMBL4620067

CN1C(=O)NC(CS)(C(C)(C)C)C1=O

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.34
CYP2C19 P33261 1/20 0.34
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4621028 0.79 RAB9A (0.34)
SCHEMBL4620211 0.78 POLB (0.33)
SCHEMBL1362594 0.69 TSHR (0.37) TSHRCYP2C19ATM
SCHEMBL4621326 0.69 TSHR (0.33) TSHRCYP2C19
SCHEMBL4620796 0.68 ADAMTS5 (0.35)
SCHEMBL4619866 0.63 TSHR (0.33) TSHRCYP2C19
SCHEMBL4620986 0.62 TYMP (0.37) TSHRCYP2C19ATM
SCHEMBL1362082 0.61 TSHR (0.36) TSHRCYP2C19ATM
SCHEMBL4618919 0.61 TSHR (0.44) TSHRCYP2C19ATM
SCHEMBL3126654 0.60 POLB (0.52) TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1883454-A2 AGENT FOR PERMANENT HAIR WAVING CONTAINING HETEROCYCLIC MERCAPTO COMPOUND Showa Denko K.K. (JP) 2008-02-06 EP disclosed
WO-2006126729-A2 AGENT FOR PERMANENT HAIR WAVING CONTAINING HETEROCYCLIC MERCAPTO COMPOUND SHOWA DENKO K.K. (JP) 2006-11-30 WO disclosed