SCHEMBL1626757

SCHEMBL1626757

CN1c2ccc(Cl)cc2C(C)(C)C12C=Nc1c(ccc3ccccc13)O2

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.77
KDM4E B2RXH2 5/20 0.77
THRB P10828 4/20 0.77
SMN1; SMN2 Q16637 4/20 0.77
ALOX12 P18054 2/20 0.77
L3MBTL1 Q9Y468 2/20 0.77
PKM P14618 1/20 0.77
HTT P42858 3/20 0.62
LMNA P02545 3/20 0.62
GAA P10253 3/20 0.62
ALDH1A1 P00352 2/20 0.62
HPGD P15428 2/20 0.62
RECQL P46063 2/20 0.62
TDP1 Q9NUW8 2/20 0.62
MAPK1 P28482 2/20 0.62
POLB P06746 1/20 0.62
NPSR1 Q6W5P4 3/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29493005 1.00 MAPT (0.77) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL4620865 0.88 MAPT (0.78) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL3439007 0.88 MAPT (0.77) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL14870331 0.88 MAPT (0.77) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL9866595 0.87 MAPT (0.58) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL23800830 0.87 MAPT (0.58) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL3162588 0.87 MAPT (0.58) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL13839771 0.87 MAPT (1.00) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL80364 0.87 MAPT (1.00) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL29493002 0.87 MAPT (1.00) MAPTKDM4ETHRBSMN1; SMN2ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11359136-B2 Colorimetric indicators for photocurable sealants THE BOEING COMPANY (US) 2022-06-14 US claimed
US-9857882-B2 Pointing display device DONGWOO FINE-CHEM CO., LTD. (KR) 2018-01-02 US claimed
US-20150079008-A1 FLUORESCENCE PLAQUE-DISCLOSANT FOR DETECTING DENTAL PLAQUE FLOSS MY HEART, LLC 2015-03-19 US claimed
US-7033581-B2 Method of treating hair with heat and a cap which provides a signal regarding treatment UNILEVER HOME & PERSONAL CARE USA DIVISION OF CONOPCO, INC. (US) 2006-04-25 US claimed
EP-1424918-B1 METHOD OF TREATING HAIR WITH HEAT AND A CAP WHICH PROVIDES A SIGNAL REGARDING TREATMENT UNILEVER PLC (GB) 2005-11-23 EP claimed
US-20050074639-A1 Method of treating hair with heat and a cap which provides a signal regarding treatment UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2005-04-07 US claimed
US-20030059459-A1 Method of treating hair with heat and a cap which provides a signal regarding treatment UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-03-27 US claimed
US-20030030040-A1 Reversibly variable photochromic color composition for articles composed of synthetic resin LUTHERN JOHN JOSEPH (US) 2003-02-13 US claimed
EP-0783130-B1 Photochromic light meter EASTMAN KODAK CO (US) 2002-03-20 EP claimed
US-5747225-A CAMERAS WITH SPIRONAPHTHOXAZINE DYES IN GELATIN LAYERS EASTMAN KODAK COMPANY (US) 1998-05-05 US claimed
EP-0783130-A1 Photochromic light meter EASTMAN KODAK COMPANY (US) 1997-07-09 EP claimed
EP-4077464-B1 FREE RADICAL POLYMERIZABLE ADHESION-PROMOTING INTERLAYER COMPOSITIONS AND METHODS OF USE PRC DESOTO INT INC (US) 2026-04-29 EP disclosed
US-12559593-B2 Dual cure sealants PRC-DESOTO INTERNATIONAL, INC. (CA) 2026-02-24 US disclosed
US-20240199911-A1 HYBRID DUAL CURE COMPOSITIONS PRC-DESOTO INTERNATIONAL, INC. (US) 2024-06-20 US disclosed
US-20240132752-A1 COMPOSITIONS CONTAINING A FREE RADICAL POLYMERIZATION INITIATOR PRC-DESOTO INTERNATIONAL, INC. (US) 2024-04-25 US disclosed
US-5551973-A LIQUID CRYSTAL GEL PHASE, MICROEMULSION PHASE XEROX CORPORATION (US) 1996-09-03 US disclosed
US-5431697-A Reversibly variable color patterning composition for synthetic resin articles MATSUI SHIKISO CHEMICAL CO., LTD. (JP) 1995-07-11 US disclosed
US-5208132-A Microencapsulation of hindered amines MATSUI SHIKISO CHEMICAL CO., LTD. (JP) 1993-05-04 US disclosed
EP-0480162-A1 Dyeing method and dyed product MATSUI SHIKISO CHEMICAL CO., LTD (JP) 1992-04-15 EP disclosed
US-4756973-A Three-dimensional network structure layer forming resin containing spirooxazine compound and phenolic resin KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1988-07-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559593-B2 Dual cure sealants DUOX2, DUOX1, GPX4 MAPT 2965/4885KDM4E 518/4885THRB 2985/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.