Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | NMT1 | P30419 | 6/20 | 0.40 |
| ▸ | NMT2 | O60551 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | GRN | P28799 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4621576 | 1.00 | BCHE (0.45) | BCHEEPHX1NMT1NMT2HPGD | |
| SCHEMBL10431763 | 0.85 | BCHE (0.44) | BCHEEPHX1NMT1NMT2HPGD | |
| SCHEMBL4620172 | 0.82 | CYP2D6 (0.43) | EPHX1HPGDKMT2AGRNSORT1 | |
| SCHEMBL3102110 | 0.82 | CYP2D6 (0.43) | EPHX1HPGDKMT2AGRNSORT1 | |
| SCHEMBL4621301 | 0.82 | CYP2D6 (0.43) | EPHX1HPGDKMT2AGRNSORT1 | |
| SCHEMBL4621464 | 0.77 | BCHE (0.46) | BCHEEPHX1HPGDMEN1KMT2A | |
| SCHEMBL4620611 | 0.77 | BCHE (0.46) | BCHEEPHX1HPGDMEN1KMT2A | |
| SCHEMBL4623637 | 0.77 | BCHE (0.46) | BCHEEPHX1HPGDMEN1KMT2A | |
| SCHEMBL10660233 | 0.77 | HPGD (0.51) | NMT1NMT2HPGDMEN1KMT2A | |
| SCHEMBL9718272 | 0.76 | CTSS (0.47) | BCHEEPHX1NMT1NMT2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1884230-A1 | PARAKERATOSIS INHIBITOR, PORE-SHRINKING AGENT OR AGENT FOR PREVENTING/AMELIORATING ROUGH SKIN AND EXTERNAL COMPOSITION FOR SKIN | Shiseido Company, Limited (JP) | 2008-02-06 | — | — | EP | disclosed |