Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4620611 | 1.00 | BCHE (0.46) | BCHEEPHX1SIGMAR1LTA4HMEN1 | |
| SCHEMBL4621464 | 1.00 | BCHE (0.46) | BCHEEPHX1SIGMAR1LTA4HMEN1 | |
| Hydrochloric Acid SCHEMBL3175437 | 0.98 | BCHE (0.45) | BCHEEPHX1SIGMAR1LTA4HMEN1 | |
| SCHEMBL28668294 | 0.88 | SIGMAR1 (0.50) | BCHEEPHX1SIGMAR1LTA4H | |
| SCHEMBL4620196 | 0.81 | LTA4H (0.47) | EPHX1LTA4HMEN1KMT2ANPC1 | |
| SCHEMBL4620202 | 0.81 | LTA4H (0.47) | EPHX1LTA4HMEN1KMT2ANPC1 | |
| SCHEMBL4619210 | 0.81 | LTA4H (0.47) | EPHX1LTA4HMEN1KMT2ANPC1 | |
| SCHEMBL22413014 | 0.79 | LTA4H (0.44) | EPHX1SIGMAR1LTA4HMEN1KMT2A | |
| SCHEMBL22413011 | 0.79 | LTA4H (0.44) | EPHX1SIGMAR1LTA4HMEN1KMT2A | |
| SCHEMBL14176596 | 0.78 | MEN1 (0.47) | BCHEEPHX1SIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1884230-A1 | PARAKERATOSIS INHIBITOR, PORE-SHRINKING AGENT OR AGENT FOR PREVENTING/AMELIORATING ROUGH SKIN AND EXTERNAL COMPOSITION FOR SKIN | Shiseido Company, Limited (JP) | 2008-02-06 | — | — | EP | disclosed |