Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NMT1 | P30419 | 5/20 | 0.37 |
| ▸ | NMT2 | O60551 | 4/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9425883 | 0.91 | CTSS (0.45) | CTSSCTSKBCHEEPHX1HDAC4 | |
| SCHEMBL9718268 | 0.82 | CTSS (0.60) | CTSSCTSKBCHEEPHX1HDAC4 | |
| SCHEMBL9718209 | 0.81 | EPHX1 (0.48) | CTSSCTSKEPHX1HDAC4HDAC1 | |
| SCHEMBL4621576 | 0.76 | BCHE (0.45) | BCHEEPHX1NMT1NMT2SIGMAR1 | |
| SCHEMBL4620970 | 0.76 | BCHE (0.45) | BCHEEPHX1NMT1NMT2SIGMAR1 | |
| SCHEMBL6799750 | 0.76 | EPHX1 (0.63) | CTSSCTSKBCHEEPHX1GAA | |
| SCHEMBL9425879 | 0.76 | CTSS (0.57) | CTSSCTSKBCHEEPHX1HDAC4 | |
| SCHEMBL10431763 | 0.75 | BCHE (0.44) | BCHEEPHX1NMT1NMT2SIGMAR1 | |
| SCHEMBL27547867 | 0.75 | CTSK (0.52) | CTSSCTSKEPHX1HDAC4HDAC1 | |
| SCHEMBL7279909 | 0.74 | HPGD (0.51) | CTSSCTSKEPHX1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153327-A | 7-Oxabicycloheptyl substituted heterocyclic amide or ester prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease | E. R. SQUIBB & SONS, INC. (US) | 1992-10-06 | — | — | US | disclosed |
| US-5100889-A | Thromboxane A2 receptor antagonists, thromboxane synthetase inhibitor | E. R. SQUIBB & SONS, INC. (US) | 1992-03-31 | — | — | US | disclosed |