SCHEMBL6153481

SCHEMBL6153481

Cc1ccc(/C=C/c2ccc3ccc4cccc5ccc2c3c45)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.47
CYP3A4 P08684 1/20 0.47
HPGD P15428 1/20 0.47
TSHR P16473 1/20 0.47
HSD17B10 Q99714 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
FGF23 Q9GZV9 1/20 0.45
NFE2L2 Q16236 6/20 0.45
GUSB P08236 2/20 0.44
CHAT P28329 2/20 0.41
PTGS1 P23219 1/20 0.39
PTGS2 P35354 1/20 0.39
TP53 P04637 1/20 0.39
MAPT P10636 1/20 0.39
KDM4E B2RXH2 1/20 0.38
NPC1 O15118 1/20 0.38
CASP3 P42574 1/20 0.38
RAB9A P51151 1/20 0.38
SENP8 Q96LD8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6153484 1.00 ALDH1A1 (0.47) ALDH1A1CYP3A4HPGDTSHRHSD17B10
SCHEMBL3474496 0.93 NFE2L2 (0.47) FGF23NFE2L2GUSBPTGS1PTGS2
SCHEMBL3474498 0.93 NFE2L2 (0.47) FGF23NFE2L2GUSBPTGS1PTGS2
SCHEMBL9099842 0.91 ALDH1A1 (0.45) ALDH1A1CYP3A4HPGDTSHRHSD17B10
SCHEMBL462098 0.91 APP (0.40) ALDH1A1CYP3A4HPGDTSHRHSD17B10
SCHEMBL2291866 0.91 PTGS2 (0.44) ALDH1A1CYP3A4HPGDTSHRHSD17B10
SCHEMBL462099 0.91 APP (0.40) ALDH1A1CYP3A4HPGDTSHRHSD17B10
SCHEMBL9407210 0.91 ALDH1A1 (0.45) ALDH1A1CYP3A4HPGDTSHRHSD17B10
SCHEMBL10050180 0.88 APP (0.46) ALDH1A1CYP3A4HPGDTSHRHSD17B10
SCHEMBL14570762 0.87 GUSB (0.37) ALDH1A1CYP3A4HPGDTSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1056140-B1 Charge injection auxiliary material IDEMITSU KOSAN CO (JP) 2005-07-06 EP disclosed
EP-0610514-B1 CHARGE INJECTION ASSISTANT AND ORGANIC ELECTROLUMINESCENCE DEVICE CONTAINING THE SAME IDEMITSU KOSAN CO (JP) 2003-04-02 EP disclosed
EP-1056140-A2 Charge injection auxiliary material IDEMITSU KOSAN COMPANY LIMITED (JP) 2000-11-29 EP disclosed
US-5536949-A ELECTROPHOTOGRAPHIC PHOTORECEPTORS IDEMISTU KOSAN CO., LTD. (JP) 1996-07-16 US disclosed
EP-0610514-A1 CHARGE INJECTION ASSISTANT AND ORGANIC ELECTROLUMINESCENCE DEVICE CONTAINING THE SAME IDEMITSU KOSAN COMPANY LIMITED (JP) 1994-08-17 EP disclosed