Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 1/20 | 0.62 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 6/20 | 0.51 |
| ▸ | MMP3 | P08254 | 4/20 | 0.51 |
| ▸ | MMP13 | P45452 | 4/20 | 0.51 |
| ▸ | MMP9 | P14780 | 3/20 | 0.50 |
| ▸ | MMP1 | P03956 | 3/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4620040 | 1.00 | ITGAV (0.62) | ITGAVMEP1BMMP2MMP3MMP13 | |
| SCHEMBL4621800 | 1.00 | ITGAV (0.62) | ITGAVMEP1BMMP2MMP3MMP13 | |
| SCHEMBL4621504 | 0.83 | MMP2 (0.66) | MMP2MMP3MMP13MMP9MMP1 | |
| SCHEMBL4619626 | 0.83 | MMP2 (0.66) | MMP2MMP3MMP13MMP9MMP1 | |
| SCHEMBL4620929 | 0.83 | MMP2 (0.66) | MMP2MMP3MMP13MMP9MMP1 | |
| SCHEMBL4620884 | 0.82 | ADAMTS4 (0.55) | ITGAVMEP1BMMP2MMP3MMP13 | |
| SCHEMBL4619809 | 0.82 | ADAMTS4 (0.55) | ITGAVMEP1BMMP2MMP3MMP13 | |
| SCHEMBL4620675 | 0.82 | ADAMTS4 (0.55) | ITGAVMEP1BMMP2MMP3MMP13 | |
| SCHEMBL30445376 | 0.82 | ITGAV (0.55) | ITGAVMEP1BMMP2MMP3MMP13 | |
| SCHEMBL1734649 | 0.80 | MMP2 (0.60) | MMP2MMP3MMP13MMP9MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1884230-A1 | PARAKERATOSIS INHIBITOR, PORE-SHRINKING AGENT OR AGENT FOR PREVENTING/AMELIORATING ROUGH SKIN AND EXTERNAL COMPOSITION FOR SKIN | Shiseido Company, Limited (JP) | 2008-02-06 | — | — | EP | disclosed |