Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.55 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.54 |
| ▸ | ITGAV | P06756 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 2/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | FLT1 | P17948 | 1/20 | 0.49 |
| ▸ | FLT4 | P35916 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 3/20 | 0.49 |
| ▸ | MMP1 | P03956 | 2/20 | 0.49 |
| ▸ | MMP3 | P08254 | 2/20 | 0.49 |
| ▸ | MMP7 | P09237 | 2/20 | 0.49 |
| ▸ | MMP13 | P45452 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4619809 | 1.00 | ADAMTS4 (0.55) | ADAMTS4MEP1BITGAVPGRFFAR4 | |
| SCHEMBL4620884 | 1.00 | ADAMTS4 (0.55) | ADAMTS4MEP1BITGAVPGRFFAR4 | |
| SCHEMBL12376754 | 0.83 | KEAP1 (0.57) | MEP1BPGRFFAR4KEAP1NFE2L2 | |
| SCHEMBL4313196 | 0.82 | MEP1B (0.51) | ADAMTS4MEP1BITGAVPGRFFAR4 | |
| SCHEMBL6774257 | 0.82 | MEP1B (0.57) | ADAMTS4MEP1BITGAVPGRFFAR4 | |
| SCHEMBL4621800 | 0.82 | ITGAV (0.62) | ADAMTS4MEP1BITGAVPGRFFAR4 | |
| SCHEMBL4620040 | 0.82 | ITGAV (0.62) | ADAMTS4MEP1BITGAVPGRFFAR4 | |
| SCHEMBL4621094 | 0.82 | ITGAV (0.62) | ADAMTS4MEP1BITGAVPGRFFAR4 | |
| SCHEMBL4621342 | 0.82 | MMP2 (0.68) | ADAMTS4SMN1; SMN2HSD17B10MMP2L3MBTL1 | |
| SCHEMBL4618694 | 0.82 | MMP2 (0.68) | ADAMTS4SMN1; SMN2HSD17B10MMP2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1884230-A1 | PARAKERATOSIS INHIBITOR, PORE-SHRINKING AGENT OR AGENT FOR PREVENTING/AMELIORATING ROUGH SKIN AND EXTERNAL COMPOSITION FOR SKIN | Shiseido Company, Limited (JP) | 2008-02-06 | — | — | EP | disclosed |