Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | LSS | P48449 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL797749 | 0.95 | FFAR1 (0.40) | PYCR1CYP2A6FFAR1FFAR4MMP2 | |
| SCHEMBL15588318 | 0.93 | FFAR1 (0.42) | PYCR1CYP2A6FFAR1FFAR4MMP2 | |
| SCHEMBL16685905 | 0.87 | GABRP (0.47) | PYCR1FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL4623168 | 0.87 | FFAR1 (0.46) | PYCR1FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL16686065 | 0.87 | MMP2 (0.38) | PYCR1CYP2A6FFAR1FFAR4MMP2 | |
| SCHEMBL24207449 | 0.84 | KDM4E (0.45) | PYCR1FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL19608720 | 0.84 | ALDH1A1 (0.48) | PYCR1FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL1897376 | 0.84 | FFAR1 (0.55) | PYCR1FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL19374612 | 0.84 | FFAR1 (0.38) | PYCR1FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL6937078 | 0.84 | FFAR1 (0.55) | PYCR1FFAR1FFAR4MMP2MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219657-B1 | POLYARYLENE AND METHOD FOR PRODUCTION THEREOF | JAPAN SCIENCE & TECH AGENCY (JP) | 2008-03-19 | — | — | EP | disclosed |
| US-6586554-B1 | Polyarylene and method for production thereof | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2003-07-01 | — | — | US | disclosed |