Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4618744 | 1.00 | LMNA (0.41) | LMNATSHRTP53PGRADRA2A | |
| SCHEMBL4621210 | 1.00 | LMNA (0.41) | LMNATSHRTP53PGRADRA2A | |
| SCHEMBL4621349 | 0.85 | PGR (0.49) | LMNATSHRTP53PGRADRA2A | |
| SCHEMBL4621225 | 0.85 | PGR (0.49) | LMNATSHRTP53PGRADRA2A | |
| SCHEMBL4618951 | 0.85 | PGR (0.49) | LMNATSHRTP53PGRADRA2A | |
| SCHEMBL4621338 | 0.84 | ALDH1A1 (0.42) | LMNATSHRTP53ALDH1A1KMT2A | |
| SCHEMBL4624373 | 0.84 | ALDH1A1 (0.42) | LMNATSHRTP53ALDH1A1KMT2A | |
| SCHEMBL4622143 | 0.84 | ALDH1A1 (0.42) | LMNATSHRTP53ALDH1A1KMT2A | |
| SCHEMBL12984130 | 0.81 | ALDH1A1 (0.47) | LMNAPGRADRA2AADRA2BHTR2A | |
| SCHEMBL28994930 | 0.76 | ALDH1A1 (0.51) | LMNATSHRPGRADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1884230-A1 | PARAKERATOSIS INHIBITOR, PORE-SHRINKING AGENT OR AGENT FOR PREVENTING/AMELIORATING ROUGH SKIN AND EXTERNAL COMPOSITION FOR SKIN | Shiseido Company, Limited (JP) | 2008-02-06 | — | — | EP | disclosed |