Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | BUB1 | O43683 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3432319 | 0.91 | USP2 (0.41) | USP2SMN1; SMN2CTSKGPR119ESR2 | |
| SCHEMBL13617428 | 0.85 | ESR2 (0.37) | USP2SMN1; SMN2CTSKBRD4HPGD | |
| SCHEMBL205421 | 0.84 | LMNA (0.48) | USP2SMN1; SMN2CTSKBRD4HPGD | |
| SCHEMBL7495565 | 0.82 | LMNA (0.47) | USP2SMN1; SMN2CTSKBRD4HPGD | |
| SCHEMBL12699827 | 0.80 | HPGD (0.37) | USP2SMN1; SMN2CTSKBRD4HPGD | |
| SCHEMBL1550544 | 0.80 | USP2 (0.41) | USP2SMN1; SMN2CTSKBRD4HPGD | |
| SCHEMBL15188491 | 0.80 | CTSK (0.44) | USP2SMN1; SMN2CTSKBRD4HPGD | |
| SCHEMBL28974037 | 0.79 | LMNA (0.41) | USP2SMN1; SMN2CTSKBRD4HPGD | |
| SCHEMBL17459686 | 0.79 | BRD4 (0.35) | USP2SMN1; SMN2CTSKBRD4HPGD | |
| SCHEMBL17459688 | 0.79 | BRD4 (0.35) | USP2SMN1; SMN2CTSKBRD4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641874-A | C for target protein degradation3The glutarimide degron body of carbon connection | C4医药公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-103561576-A | Heterocyclic modulators of lipid synthesis | 3 V BIOSCIENCES INC | 2014-02-05 | — | — | CN | disclosed |
| CN-101821256-A | Novel heterocyclic compounds as mGlu5 antagonists | RECORDATI IRELAND LTD | 2010-09-01 | — | — | CN | disclosed |
| EP-1897956-A1 | Process for preparation of optically active amines by optical resolution of racemic amines employing a bacterial omega-transaminase | Lonza AG (CH) | 2008-03-12 | — | — | EP | disclosed |