Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 4/20 | 0.50 |
| ▸ | MMP13 | P45452 | 3/20 | 0.50 |
| ▸ | MMP8 | P22894 | 3/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP7 | P09237 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 2/20 | 0.47 |
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 5/20 | 0.44 |
| ▸ | MMP9 | P14780 | 4/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | PKLR | P30613 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4623983 | 1.00 | MMP12 (0.50) | MMP12MMP13MMP8MMP1MMP7 | |
| SCHEMBL4619148 | 1.00 | MMP12 (0.50) | MMP12MMP13MMP8MMP1MMP7 | |
| Alanine SCHEMBL7615581 | 0.92 | PLG (0.46) | MMP12MMP13MMP8MMP1MMP7 | |
| SCHEMBL5966471 | 0.88 | MMP2 (0.58) | MMP12MMP13MMP8MMP1MMP7 | |
| SCHEMBL5966474 | 0.88 | MMP2 (0.58) | MMP12MMP13MMP8MMP1MMP7 | |
| SCHEMBL7371687 | 0.86 | MMP8 (0.49) | MMP12MMP13MMP8MMP1MMP7 | |
| Hydrochloric Acid SCHEMBL7650690 | 0.85 | MMP8 (0.48) | MMP12MMP13MMP8MMP1MMP7 | |
| SCHEMBL2820939 | 0.84 | SLC1A3 (0.59) | MMP13MMP8MMP1ITGB3ITGA2B | |
| SCHEMBL7160235 | 0.84 | SLC1A3 (0.59) | MMP13MMP8MMP1ITGB3ITGA2B | |
| SCHEMBL7402563 | 0.84 | SLC1A3 (0.59) | MMP13MMP8MMP1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1884230-A1 | PARAKERATOSIS INHIBITOR, PORE-SHRINKING AGENT OR AGENT FOR PREVENTING/AMELIORATING ROUGH SKIN AND EXTERNAL COMPOSITION FOR SKIN | Shiseido Company, Limited (JP) | 2008-02-06 | — | — | EP | disclosed |
| WO-2002014349-A2 | NON-COVALENT INHIBITORS OF UROKINASE AND BLOOD VESSEL FORMATION | CORVAS INTERNATIONAL, INC. (US) | 2002-02-21 | — | — | WO | disclosed |
| EP-1100814-A2 | INHIBITORS OF UROKINASE AND BLOOD VESSEL FORMATION | CORVAS INTERNATIONAL, INC. (US) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000005245-A2 | INHIBITORS OF UROKINASE AND BLOOD VESSEL FORMATION | CORVAS INTERNATIONAL, INC. (US) | 2000-02-03 | — | — | WO | disclosed |