Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 6/20 | 0.46 |
| ▸ | CES1 | P23141 | 5/20 | 0.46 |
| ▸ | DGKA | P23743 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 5/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9095203 | 1.00 | CES2 (0.46) | CES2CES1DGKAFAAHCA12 | |
| SCHEMBL9094766 | 1.00 | CES2 (0.46) | CES2CES1DGKAFAAHCA12 | |
| SCHEMBL9097583 | 1.00 | CES2 (0.46) | CES2CES1DGKAFAAHCA12 | |
| SCHEMBL9095001 | 1.00 | CES2 (0.46) | CES2CES1DGKAFAAHCA12 | |
| SCHEMBL27986037 | 1.00 | CES2 (0.46) | CES2CES1DGKAFAAHCA12 | |
| SCHEMBL9097097 | 1.00 | CES2 (0.46) | CES2CES1DGKAFAAHCA12 | |
| SCHEMBL9097723 | 1.00 | CES2 (0.46) | CES2CES1DGKAFAAHCA12 | |
| SCHEMBL28682840 | 0.98 | CES2 (0.45) | CES2CES1DGKAFAAHCA12 | |
| SCHEMBL28411960 | 0.98 | CES2 (0.45) | CES2CES1DGKAFAAHCA12 | |
| SCHEMBL29047527 | 0.98 | CES2 (0.45) | CES2CES1DGKAFAAHCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101071281-B | Toner | RICOH KK | 2011-09-07 | — | — | CN | disclosed |
| EP-1369105-B1 | Use and method for dyeing hair | KAO CORP (JP) | 2008-03-19 | — | — | EP | disclosed |
| EP-1398022-B1 | Method of dyeing hair characterised by use of an azo dye containing a dissociative proton | KAO CORP (JP) | 2008-03-19 | — | — | EP | disclosed |
| CN-101071281-A | Toner | RICOH KK (JP) | 2007-11-14 | — | — | CN | disclosed |
| EP-1240892-B1 | Hair colouring method and composition comprising a ring-fused heterocycle direct dyestuff | KAO CORP (JP) | 2007-05-09 | — | — | EP | disclosed |
| EP-1275367-B1 | Hair coloring composition comprising pyrazoloazole compounds | KAO CORP (JP) | 2006-11-29 | — | — | EP | disclosed |
| US-7083655-B2 | Hair dye composition | KAO CORPORATION (JP) | 2006-08-01 | — | — | US | disclosed |
| US-7056355-B2 | Hair dye composition and dyeing method | KAO CORPORATION (JP) | 2006-06-06 | — | — | US | disclosed |
| US-20050015896-A1 | Hair dye composition and dyeing method | KAO CORPORATION (JP) | 2005-01-27 | — | — | US | disclosed |
| US-6783558-B2 | USING A COMPOSITION COMPRISING A SPECIFIED RING-FUSED HETEROCYCLE DIRECT DYESTUFF; LONG LASTING BRILLIANT COLORS STABLE AGAINST WASHING | KAO CORPORATION (JP) | 2004-08-31 | — | — | US | disclosed |
| US-20030024059-A1 | Hair colouring method and composition | KAO CORPORATION (JP) | 2003-02-06 | — | — | US | disclosed |
| EP-1275367-A1 | Hair coloring composition comprising pyrazoloazole compounds | KAO CORPORATION (JP) | 2003-01-15 | — | — | EP | disclosed |
| EP-1240892-A2 | Hair colouring method and composition comprising a ring-fused heterocycle direct dyestuff | Kao Corporation (JP) | 2002-09-18 | — | — | EP | disclosed |
| CN-1081951-C | Use of ion exchange resins loaded with quioolonecarboxylic acid derivatives | BAYER AG (DE) | 2002-04-03 | — | — | CN | disclosed |
| CN-1054040-C | Preparation of ion exchange resins carrying quinolone carboxylic acid derivatives | BAYER AG (DE) | 2000-07-05 | — | — | CN | disclosed |
| CN-1046302-C | Particle adsorption method | ROHM & HAAS (US) | 1999-11-10 | — | — | CN | disclosed |
| CN-1108968-A | Use of ion exchange resins loaded with quioolonecarboxylic acid derivatives | BAYER AG (DE) | 1995-09-27 | — | — | CN | disclosed |
| CN-1097781-A | Be used to improve the water-fast multistage latex that causes the performance that bleaches of water base paint compositions | ROHM & HAAS (US) | 1995-01-25 | — | — | CN | disclosed |
| CN-1073959-A | Particle adsorption method | ROHM & HAAS (US) | 1993-07-07 | — | — | CN | disclosed |
| CN-88103473-A | Preparation and application of ion exchange resin loaded with quinolone carboxylic acid derivative | — | 1988-12-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030024059-A1 | Hair colouring method and composition | TYR, SHH, CYBB | CES2 1808/4885CES1 3599/4885DGKA 2430/4885 |
| US-20050015896-A1 | Hair dye composition and dyeing method | SULT1A1, CYP21A2, SULT2A1 | CES2 2167/4885CES1 1484/4885DGKA 4213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.