Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.77 |
| ▸ | SYK | P43405 | 9/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mephenoxalone SCHEMBL935967 | 1.00 | PKM (0.77) | PKMSYKADRA2CLMNAMAOA | |
| Mephenoxalone SCHEMBL5392 | 1.00 | PKM (0.77) | PKMSYKADRA2CLMNAMAOA | |
| Mephenoxalone SCHEMBL1061349 | 0.99 | PKM (0.75) | PKMSYKADRA2CLMNAMAOA | |
| Mephenoxalone SCHEMBL22472152 | 0.99 | PKM (0.75) | PKMSYKADRA2CLMNAMAOA | |
| Mephenoxalone SCHEMBL7938104 | 0.99 | PKM (0.75) | PKMSYKADRA2CLMNAMAOA | |
| Mephenoxalone SCHEMBL7117835 | 0.99 | PKM (0.75) | PKMSYKADRA2CLMNAMAOA | |
| Mephenoxalone SCHEMBL2175454 | 0.99 | PKM (0.75) | PKMSYKADRA2CLMNAMAOA | |
| Mephenoxalone SCHEMBL6098064 | 0.99 | PKM (0.75) | PKMSYKADRA2CLMNAMAOA | |
| Mephenoxalone SCHEMBL1969509 | 0.99 | PKM (0.75) | PKMSYKADRA2CLMNAMAOA | |
| Mephenoxalone SCHEMBL6492968 | 0.97 | PKM (0.73) | PKMSYKADRA2CLMNAMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948643-A2 | 3-ALKYL-5- (4-ALKYL-5-OXO-TETRAHYDROFURAN-2-YL) PYRROLIDIN-2-ONE DERIVATIVES AS INTERMEDIATES IN THE SYNTHESIS OF RENIN INHIBITORS | Novartis AG (CH) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007138381-A2 | PHOSPHONATED OXAZOLIDINONES AND USES THEREOF FOR THE PREVENTION AND TREATMENT OF BONE AND JOINT INFECTIONS | TARGANTA THERAPEUTICS INC. (CA) | 2007-12-06 | — | — | WO | disclosed |
| WO-2007045420-A2 | 3-ALKYL-5- (4-ALKYL-5-OXO-TETRAHYDROFUTRAN-2-YL) PYRROLIDIN-2-ONE DERIVATIVES AS INTERMEDIATES IN THE SYNTHESIS OF RENIN INHIBITORS | NOVARTIS AG (CH) | 2007-04-26 | — | — | WO | disclosed |
| EP-1144751-A2 | SOIL-RESISTANT SPIN FINISH COMPOSITIONS | 3M Innovative Properties Company (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000041500-A2 | SOIL-RESISTANT SPIN FINISH COMPOSITIONS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-07-20 | — | — | WO | disclosed |