Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.75 |
| ▸ | SYK | P43405 | 9/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mephenoxalone SCHEMBL4621926 | 0.99 | PKM (0.77) | PKMSYKADRA2CLMNAMAOA | |
| Mephenoxalone SCHEMBL935967 | 0.99 | PKM (0.77) | PKMSYKADRA2CLMNAMAOA | |
| Mephenoxalone SCHEMBL5392 | 0.99 | PKM (0.77) | PKMSYKADRA2CLMNAMAOA | |
| Mephenoxalone SCHEMBL1061349 | 0.97 | PKM (0.75) | PKMSYKADRA2CLMNAMAOA | |
| Mephenoxalone SCHEMBL22472152 | 0.97 | PKM (0.75) | PKMSYKADRA2CLMNAMAOA | |
| Mephenoxalone SCHEMBL7938104 | 0.97 | PKM (0.75) | PKMSYKADRA2CLMNAMAOA | |
| Mephenoxalone SCHEMBL2175454 | 0.97 | PKM (0.75) | PKMSYKADRA2CLMNAMAOA | |
| Mephenoxalone SCHEMBL6098064 | 0.97 | PKM (0.75) | PKMSYKADRA2CLMNAMAOA | |
| Mephenoxalone SCHEMBL1969509 | 0.97 | PKM (0.75) | PKMSYKADRA2CLMNAMAOA | |
| Mephenoxalone SCHEMBL6492968 | 0.96 | PKM (0.73) | PKMSYKADRA2CLMNAMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030216374-A1 | Antibiotic oxazolidinone derivatives | SYNGENTA LIMITED (GB) | 2003-11-20 | — | — | US | disclosed |
| US-6605630-B1 | Active against drug resistant gram positive pathogens | SYNGENTA LIMITED (GB) | 2003-08-12 | — | — | US | disclosed |
| EP-1005468-A1 | ANTIBIOTIC OXAZOLIDINONE DERIVATIVES | ZENECA LIMITED (GB) | 2000-06-07 | — | — | EP | disclosed |
| WO-1999010342-A1 | ANTIBIOTIC OXAZOLIDINONE DERIVATIVES | ZENECA LIMITED (GB) | 1999-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216374-A1 | Antibiotic oxazolidinone derivatives | OXA1L, HRH1, OGDH | PKM 4284/4885SYK 2294/4885ADRA2C 415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.