Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | TPH1 | P17752 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4621962 | 0.89 | MMP12 (0.40) | TRIM24TRIM33F10F2PRSS1 | |
| SCHEMBL3591193 | 0.79 | ADAMTS4 (0.41) | AOC3MMP2MMP9HSD17B1HSD17B2 | |
| SCHEMBL3577149 | 0.76 | FFAR1 (0.48) | F2BCL2 | |
| SCHEMBL3584964 | 0.74 | F7 (0.44) | F10F2ERN1HSD17B2 | |
| SCHEMBL4363950 | 0.74 | MMP12 (0.42) | AOC3MMP2MMP9ALDH1A1 | |
| SCHEMBL4649130 | 0.72 | MMP2 (0.40) | TPH1MMP2MMP9ALDH1A1MAPT | |
| SCHEMBL3595967 | 0.71 | HSD17B2 (0.50) | HSD17B2 | |
| SCHEMBL6182236 | 0.69 | HSD17B2 (0.62) | AOC3ERN1HSD17B1HSD17B2BCHE | |
| SCHEMBL25214984 | 0.69 | MAPT (0.43) | BCHEALDH1A1MAPTHPGD | |
| SCHEMBL25195471 | 0.69 | MAPT (0.43) | BCHEALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902014-A2 | GLUTAMATE AGGRECANASE INHIBITORS | Wyeth (US) | 2008-03-26 | — | — | EP | disclosed |
| WO-2007008994-A2 | GLUTAMATE AGGRECANASE INHIBITORS | WYETH (US) | 2007-01-18 | — | — | WO | disclosed |