SCHEMBL4622185

SCHEMBL4622185

CCC(CC)CCn1cnc2c(=O)[nH]c(=O)[nH]c21

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNP P00491 1/20 0.49
GAA P10253 1/20 0.36
KMT2A Q03164 3/20 0.36
ALDH1A1 P00352 2/20 0.36
KDM4E B2RXH2 1/20 0.36
HSD17B10 Q99714 1/20 0.36
PDE2A O00408 1/20 0.35
GDA Q9Y2T3 1/20 0.35
MEN1 O00255 2/20 0.35
HPRT1 P00492 1/20 0.34
LMNA P02545 1/20 0.33
CYP3A4 P08684 1/20 0.33
NFKB1 P19838 1/20 0.33
BLM P54132 1/20 0.33
VCP P55072 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HIF1A Q16665 1/20 0.33
PDE1A P54750 1/20 0.33
PDE1B Q01064 1/20 0.33
PDE1C Q14123 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8884657 0.86 PNP (0.51) PNPGAAKMT2AALDH1A1KDM4E
SCHEMBL5054173 0.84 PNP (0.54) PNPGAAKMT2AALDH1A1KDM4E
SCHEMBL16488940 0.82 PNP (0.43) PNPKMT2AALDH1A1HSD17B10MEN1
SCHEMBL6233163 0.81 PNP (0.58) PNPGAAKMT2AALDH1A1KDM4E
SCHEMBL380137 0.81 PNP (0.50) PNPGAAKMT2AALDH1A1GDA
SCHEMBL7217325 0.79 PNP (0.49) PNPGAAKMT2AALDH1A1GDA
SCHEMBL3489068 0.79 PNP (0.44) PNPGAAKMT2AALDH1A1PDE2A
SCHEMBL11661807 0.79 PNP (0.62) PNPGAAKMT2AALDH1A1KDM4E
SCHEMBL28702160 0.78 PNP (0.54) PNPGAAKMT2AALDH1A1GDA
SCHEMBL7530556 0.78 PNP (0.57) PNPKMT2AALDH1A1HSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1904020-A2 NEW SLIMMING COSMETIC COMPOSITIONS Sederma S.A.S. (FR) 2008-04-02 EP disclosed
WO-2007010478-A2 SLIMMING COSMETIC COMPOSITIONS SEDERMA (FR) 2007-01-25 WO disclosed
EP-1497444-A4 METHODS FOR INCREASING POLYPEPTIDE PRODUCTION IMMUNEX CORP (US) 2006-08-30 EP disclosed
EP-1497444-A2 METHODS FOR INCREASING POLYPEPTIDE PRODUCTION Immunex Corporation (US) 2005-01-19 EP disclosed
WO-2003083066-A2 METHODS FOR INCREASING POLYPEPTIDE PRODUCTION IMMUNEX CORPORATION (US) 2003-10-09 WO disclosed