SCHEMBL8884657

SCHEMBL8884657

CC(C)CCn1cnc2c(=O)[nH]c(=O)[nH]c21

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PNP P00491 1/20 0.51
ALDH1A1 P00352 5/20 0.44
KDM4E B2RXH2 2/20 0.44
HSD17B10 Q99714 1/20 0.44
HTT P42858 1/20 0.40
KMT2A Q03164 3/20 0.39
MEN1 O00255 1/20 0.39
RAB9A P51151 3/20 0.38
GDA Q9Y2T3 1/20 0.36
DAO P14920 1/20 0.36
NPC1 O15118 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TSHR P16473 2/20 0.36
LMNA P02545 1/20 0.36
HPGD P15428 1/20 0.36
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7416953 0.86 ALDH1A1 (0.47) PNPALDH1A1KDM4EHSD17B10HTT
SCHEMBL4622185 0.86 PNP (0.49) PNPALDH1A1KDM4EHSD17B10KMT2A
SCHEMBL3141045 0.86 KMT2A (0.43) PNPALDH1A1KDM4EHSD17B10HTT
SCHEMBL60160 0.85 PNP (0.47) PNPALDH1A1KDM4EHSD17B10KMT2A
SCHEMBL5054173 0.83 PNP (0.54) PNPALDH1A1KDM4EKMT2AMEN1
SCHEMBL27256850 0.82 PNP (0.55) PNPALDH1A1KDM4EHSD17B10KMT2A
SCHEMBL6233163 0.81 PNP (0.58) PNPALDH1A1KDM4EKMT2AMEN1
SCHEMBL7530556 0.80 PNP (0.57) PNPALDH1A1HSD17B10KMT2AMEN1
SCHEMBL27414457 0.80 PNP (0.54) PNPALDH1A1KMT2AGDAGAA
SCHEMBL28702160 0.80 PNP (0.54) PNPALDH1A1KMT2AGDAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5700369-A Process for adsorboaggregational flotation of Carlin type natural gold ore dressing GUANGZHOU INSTITUTE OF GEOCHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) 1997-12-23 US claimed
US-5700369-A Process for adsorboaggregational flotation of Carlin type natural gold ore dressing GUANGZHOU INSTITUTE OF GEOCHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) 1997-12-23 US disclosed