Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.44 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | VCP | P55072 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL60160 | 0.87 | PNP (0.47) | PNPGDAKMT2AMEN1ALDH1A1 | |
| SCHEMBL7419700 | 0.86 | ALDH1A1 (0.46) | PNPKMT2AGAAALDH1A1CCNE2 | |
| SCHEMBL7326970 | 0.84 | PNP (0.48) | PNPGDAHPRT1KMT2AMEN1 | |
| SCHEMBL380137 | 0.82 | PNP (0.50) | PNPGDAKMT2AGAAALDH1A1 | |
| SCHEMBL7217325 | 0.80 | PNP (0.49) | PNPGDAKMT2AGAAALDH1A1 | |
| SCHEMBL16488940 | 0.80 | PNP (0.43) | PNPHPRT1KMT2AMEN1ALDH1A1 | |
| SCHEMBL5054173 | 0.79 | PNP (0.54) | PNPGDAKMT2AMEN1GAA | |
| SCHEMBL4622185 | 0.79 | PNP (0.49) | PNPGDAHPRT1KMT2AMEN1 | |
| SCHEMBL8884657 | 0.78 | PNP (0.51) | PNPGDAKMT2AMEN1GAA | |
| SCHEMBL295964 | 0.78 | KDM4E (0.42) | KMT2AMEN1GAAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100062038-A1 | Markers, Antibodies and Recombinant scFvs for Mesenchymal Stem Cell Sub-populations and Osteoclasts | NATIONAL UNIVERSITY OF IRELAND, GALWAY (IE) | 2010-03-11 | — | — | US | disclosed |
| EP-2118272-A2 | MARKERS, ANTIBODIES AND RECOMBINANT SCFVS FOR MESENCHYMAL STEM CELL-SUB-POPULATIONS AND OSTEOCLASTS | National University of Ireland, Galway (IE) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008110578-A2 | MARKERS, ANTIBODIES AND RECOMBINANT SCFVS FOR MESENCHYMAL STEM CELL-SUB-POPULATIONS AND OSTEOCLASTS | NATIONAL UNIVERSITY OF IRELAND, GALWAY (IE) | 2008-09-18 | — | — | WO | disclosed |
| US-20060094013-A1 | Salt-inducible kinases 2 and use thereof | TAKEMORI, HIROSHI (JP) | 2006-05-04 | — | — | US | disclosed |
| EP-1468078-A1 | METHOD AND DEVICE FOR IDENTIFYING SUBSTANCES CAPABLE OF MODULATING ADIPOCYTE DIFFERENTIATION | Genfit (FR) | 2004-10-20 | — | — | EP | disclosed |
| WO-2003060106-A1 | METHOD AND DEVICE FOR IDENTIFYING SUBSTANCES CAPABLE OF MODULATING ADIPOCYTE DIFFERENTIATION | GENFIT (FR) | 2003-07-24 | — | — | WO | disclosed |