Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1025648 | 0.82 | HCAR2 (0.43) | HCAR2ADRA2AADRA2CADRA2BTAAR1 | |
| SCHEMBL15302056 | 0.81 | HCAR2 (0.41) | HCAR2ADRA2AADRA2CADRA2BTAAR1 | |
| SCHEMBL3179891 | 0.76 | HCAR2 (0.38) | HCAR2ADRA2AADRA2CADRA2BTAAR1 | |
| SCHEMBL3815492 | 0.76 | HCAR2 (0.38) | HCAR2ADRA2AADRA2CADRA2BTAAR1 | |
| SCHEMBL17862086 | 0.76 | HCAR2 (0.38) | HCAR2ADRA2AADRA2CADRA2BTAAR1 | |
| SCHEMBL15301527 | 0.74 | HCAR2 (0.41) | HCAR2ADRA2AADRA2CADRA2BTAAR1 | |
| SCHEMBL15302408 | 0.74 | TAAR1 (0.39) | HCAR2ADRA2AADRA2CADRA2BTAAR1 | |
| SCHEMBL27562681 | 0.74 | TAAR1 (0.35) | TAAR1TRPA1LMNAALDH1A1SCN1A | |
| SCHEMBL27560166 | 0.74 | KDM4E (0.33) | HCAR2ADRA2AADRA2CTAAR1TRPA1 | |
| Hydrogen Sulfide SCHEMBL27817796 | 0.73 | THRB (0.44) | HCAR2ADRA2AADRA2CADRA2BTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7459577-B2 | Reacting a chlorosilane with grignard reagent | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2008-12-02 | — | — | US | disclosed |
| US-20050070730-A1 | Production processes for triorganomonoalkoxysilanes and triorganomonochlorosilanes | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070730-A1 | Production processes for triorganomonoalkoxysilanes and triorganomonochlorosilanes | MLX, HAX1, GRIA3 | HCAR2 354/4885ADRA2A 2324/4885ADRA2C 3616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.