Sugi Predict

Sugi Predict / Compounds / SCHEMBL4592722

SCHEMBL4592722

SCHEMBL4592722

C[n+]1c(Cl)ccc2ccccc21

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ ACHE P22303 14/20 0.49
▸ KMT2A Q03164 5/20 0.42
▸ POLB P06746 4/20 0.42
▸ BCHE P06276 5/20 0.39
▸ MEN1 O00255 3/20 0.39
▸ MAPT P10636 2/20 0.39
▸ SMN1; SMN2 Q16637 2/20 0.39
▸ NPC1 O15118 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ THRB P10828 1/20 0.39
▸ PKM P14618 1/20 0.39
▸ MAPK1 P28482 1/20 0.39
▸ HTT P42858 1/20 0.39
▸ RECQL P46063 1/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ BLM P54132 1/20 0.39
▸ NPSR1 Q6W5P4 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9205826 0.98 ACHE (0.47) ACHEKMT2APOLBBCHEMEN1
Iodide SCHEMBL18497004 0.98 ACHE (0.51) ACHEKMT2APOLBBCHEMEN1
SCHEMBL2824489 0.92 ACHE (0.44) ACHEKMT2APOLBBCHEMEN1
SCHEMBL34461983 0.92 ACHE (0.44) ACHEKMT2APOLBBCHEMEN1
SCHEMBL6744860 0.89 ACHE (0.42) ACHEKMT2APOLBBCHEMEN1
Trifluoromethanesulfonic Acid SCHEMBL31472680 0.82 KCNH2 (0.41) ACHEKDM4EALDH1A1
Trifluoromethanesulfonic Acid SCHEMBL4497025 0.82 KCNH2 (0.41) ACHEKDM4EALDH1A1
SCHEMBL30929898 0.74 ACHE (0.47) ACHEKMT2APOLBBCHEMEN1
SCHEMBL1044982 0.74 ACHE (0.47) ACHEKMT2APOLBBCHEMEN1
SCHEMBL6333940 0.74 CYP2A6 (0.41) ACHEKMT2AMEN1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6977001-B2 Dye compositions containing quinolinium salts WELLA AG (DE) 2005-12-20 — — US claimed
US-20030196281-A1 1-benzopyrane-derivatives and colouring agents containing the salts thereof WELLA AKTIENGESELLSCHAFT (DE) 2003-10-23 — — US claimed
US-20030177592-A1 Dye compositions containing quinolinium salts HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2003-09-25 — — US claimed
EP-3862431-B1 METHOD FOR PRODUCING HAIRPIN SINGLE-STRAND RNA MOLECULES TORAY INDUSTRIES (JP) 2024-06-26 — — EP disclosed
US-20240110186-A1 METHOD OF PRODUCING HAIRPIN SINGLE-STRANDED RNA MOLECULES TORAY INDUSTRIES, INC. (JP) 2024-04-04 — — US disclosed
US-11891602-B2 Method of producing hairpin single-stranded RNA molecules TORAY INDUSTRIES, INC. (JP) 2024-02-06 — — US disclosed
US-20230158146-A1 HSP70 Inhibitors and Methods of Using Same THE WISTAR INST (US) 2023-05-25 — — US disclosed
US-20230158146-A1 HSP70 Inhibitors and Methods of Using Same THE WISTAR INST (US) 2023-05-25 — — US disclosed
US-20210317495-A1 METHOD OF PRODUCING HAIRPIN SINGLE-STRANDED RNA MOLECULES TORAY INDUSTRIES, INC. (JP) 2021-10-14 — — US disclosed
EP-3862431-A1 METHOD FOR PRODUCING HAIRPIN SINGLE-STRAND RNA MOLECULES Toray Industries, Inc. (JP) 2021-08-11 — — EP disclosed
CN-112673102-A Preparation method of hairpin type single-stranded RNA molecule 东丽株式会社 2021-04-16 — — CN disclosed
US-20090234151-A1 Preparation of Mono-/Difluorinated Hydrocarbon Compounds RHODIA CHIMIE (FR) 2009-09-17 — — US disclosed
EP-1904425-A1 METHOD FOR PREPARING MONO- OR DIFLUORINATED HYDROCARBON COMPOUNDS Rhodia Chimie SA (FR) 2008-04-02 — — EP disclosed
EP-1891001-A1 SULFONAMIDE DERIVATIVES USEFUL AS LIVER CARNITINE PALMITOYL TRANSFERASE (L-CPTl) INHIBITORS F. Hoffmann-Roche AG (CH) 2008-02-27 — — EP disclosed
WO-2007010111-A1 METHOD FOR PREPARING MONO- OR DIFLUORINATED HYDROCARBON COMPOUNDS RHODIA CHIMIE (FR) 2007-01-25 — — WO disclosed
WO-2007010111-A1 METHOD FOR PREPARING MONO- OR DIFLUORINATED HYDROCARBON COMPOUNDS RHODIA CHIMIE (FR) 2007-01-25 — — WO disclosed
WO-2006131452-A1 SULFONAMIDE DERIVATIVES USEFUL AS LIVER CARNITINE PALMITOYL TRANSFERASE (L-CPTl) INHIBITORS F. HOFFMANN-LA ROCHE AG (CH) 2006-12-14 — — WO disclosed
US-6977001-B2 Dye compositions containing quinolinium salts WELLA AG (DE) 2005-12-20 — — US disclosed
US-20030196281-A1 1-benzopyrane-derivatives and colouring agents containing the salts thereof WELLA AKTIENGESELLSCHAFT (DE) 2003-10-23 — — US disclosed
US-20030177592-A1 Dye compositions containing quinolinium salts HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2003-09-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090234151-A1 Preparation of Mono-/Difluorinated Hydrocarbon Compounds AHR, CYP2E1, CYP2F1 ACHE 3533/4885KMT2A 614/4885POLB 137/4885
US-20230158146-A1 HSP70 Inhibitors and Methods of Using Same HSPA2, HSPBP1, HSP90AB1 ACHE 3194/4885KMT2A 2724/4885POLB 2670/4885
US-20030196281-A1 1-benzopyrane-derivatives and colouring agents containing the salts thereof KRT18, COL2A1, PHB1 ACHE 4265/4885KMT2A 1669/4885POLB 1150/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.