Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | AKT1 | P31749 | 2/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | CDC25A | P30304 | 1/20 | 0.53 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.50 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | PRKCG | P05129 | 1/20 | 0.41 |
| ▸ | PRKCB | P05771 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | PRKCH | P24723 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethyl Hydrogen Phosphate SCHEMBL625867 | 0.92 | LMNA (0.46) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL19821338 | 0.90 | LMNA (0.45) | LMNAAKT1ESR1ADORA3CDC25A | |
| Tetrabuthylammonium SCHEMBL26929180 | 0.88 | SLC22A1 (0.50) | LMNAAKT1ESR1ADORA3CDC25A | |
| Tetrabuthylammonium SCHEMBL29773383 | 0.86 | SLC22A1 (0.48) | LMNAAKT1ESR1ADORA3CDC25A | |
| Tetrabuthylammonium SCHEMBL29773382 | 0.86 | SLC22A1 (0.48) | LMNAAKT1ESR1ADORA3CDC25A | |
| Tetrabuthylammonium SCHEMBL5144551 | 0.86 | SLC22A1 (0.48) | LMNAAKT1ESR1ADORA3CDC25A | |
| Tetrabuthylammonium SCHEMBL6382222 | 0.86 | AKT1 (0.66) | LMNAAKT1ESR1ADORA3CDC25A | |
| Tributylmethylammonium SCHEMBL3267256 | 0.86 | LMNA (0.51) | LMNAAKT1ESR1ADORA3CDC25A | |
| Tetrabuthylammonium SCHEMBL19834900 | 0.84 | SLC22A1 (0.71) | LMNAAKT1ESR1ADORA3CDC25A | |
| Tetrabuthylammonium SCHEMBL49814 | 0.84 | SLC22A1 (0.71) | LMNAAKT1ESR1ADORA3CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240190875-A1 | SPIROINDOLINE DERIVATIVE, AND PREPARATION METHOD AND MEDICAL USE THEREOF | CHANGCHUN GENESCIENCE PHARMACEUTICAL CO., LTD. (CN) | 2024-06-13 | — | — | US | disclosed |
| WO-2023238500-A1 | TREATMENT AGENT FOR CARBON FIBER PRECURSOR, AND CARBON FIBER PRECURSOR | 竹本油脂株式会社 | 2023-12-14 | — | — | WO | disclosed |
| CN-117157295-A | Indoline-containing spiro derivative, preparation method and medical application thereof | 长春金赛药业有限责任公司 | 2023-12-01 | — | — | CN | disclosed |
| EP-4282867-A1 | INDOLINE-CONTAINING SPIRO DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN MEDICINE | Changchun Genescience Pharmaceutical Co., Ltd. (CN) | 2023-11-29 | — | — | EP | disclosed |
| WO-2022228318-A1 | INDOLINE-CONTAINING SPIRO DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN MEDICINE | 长春金赛药业有限责任公司 | 2022-11-03 | — | — | WO | disclosed |
| US-8791129-B2 | Phenylquinazoline derivatives | MERCK PATENT GMBH (DE) | 2014-07-29 | — | — | US | disclosed |
| US-20130178443-A1 | PHENYLQUINAZOLINE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-07-11 | — | — | US | disclosed |
| EP-1554327-B1 | CELLULAR POLYURETHANE ELASTOMERS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF | BAYER MATERIALSCIENCE AG (DE) | 2008-03-26 | — | — | EP | disclosed |
| EP-1554327-A1 | CELLULAR POLYURETHANE ELASTOMERS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF | Bayer MaterialScience AG (DE) | 2005-07-20 | — | — | EP | disclosed |
| WO-2004035648-A1 | CELLULAR POLYURETHANE ELASTOMERS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF | BAYER MATERIALSCIENCE AG (DE) | 2004-04-29 | — | — | WO | disclosed |
| US-20040077740-A1 | Cellular polyurethane elastomers, a process for preparing these and their use | BAYER AKTIENGESELLSCHAFT (DE) | 2004-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240190875-A1 | SPIROINDOLINE DERIVATIVE, AND PREPARATION METHOD AND MEDICAL USE THEREOF | GHSR, GHRHR, NR3C2 | LMNA 1688/4885AKT1 645/4885ESR1 891/4885 |
| US-20130178443-A1 | PHENYLQUINAZOLINE DERIVATIVES | HSP90B1, HSP90AB1, HSP90AA1 | LMNA 2423/4885AKT1 2286/4885ESR1 3142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.