Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 12/20 | 0.68 |
| ▸ | PDE1A | P54750 | 3/20 | 0.68 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.68 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | BLM | P54132 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | PDE2A | O00408 | 3/20 | 0.58 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3860921 | 0.85 | ALDH1A1 (0.65) | CYP1A2CYP2C19CYP3A4ALDH1A1 | |
| SCHEMBL9160664 | 0.82 | PDE5A (0.44) | PDE5APDE1APDE1BPDE1CCYP1A2 | |
| SCHEMBL10960178 | 0.81 | PDE5A (0.70) | PDE5APDE1APDE1BPDE1CCYP1A2 | |
| SCHEMBL7089133 | 0.81 | PDE5A (0.70) | PDE5APDE1APDE1BPDE1CCYP1A2 | |
| SCHEMBL4622439 | 0.81 | PDE5A (0.73) | PDE5APDE1APDE1BPDE1CCYP1A2 | |
| SCHEMBL7402437 | 0.80 | PDE5A (0.97) | PDE5APDE1APDE1BPDE1CCYP1A2 | |
| SCHEMBL2917588 | 0.80 | PDE5A (0.74) | PDE5APDE1APDE1BPDE1CCYP1A2 | |
| SCHEMBL14889319 | 0.76 | PDE5A (1.00) | PDE5APDE1APDE1BPDE1CCYP1A2 | |
| SCHEMBL3390598 | 0.74 | CYP1A2 (0.60) | PDE5APDE1APDE1BPDE1CCYP1A2 | |
| SCHEMBL897036 | 0.74 | PDE1A (1.00) | PDE5APDE1APDE1BPDE1CCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0502043-B1 | UTILIZATION OF XANTHINES, OPTIONALLY INCORPORATED IN LIPOSOMES IN ORDER TO HELP THE PIGMENTATION OF SKIN OR HAIR | LVMH RECH (FR) | 1995-03-01 | — | — | EP | claimed |
| EP-0502043-A1 | UTILIZATION OF XANTHINES, OPTIONALLY INCORPORATED IN LIPOSOMES IN ORDER TO HELP THE PIGMENTATION OF SKIN OR HAIR. | LVMH RECH (FR) | 1992-09-09 | — | — | EP | claimed |
| WO-1991007945-A1 | UTILIZATION OF XANTHINES, OPTIONALLY INCORPORATED IN LIPOSOMES IN ORDER TO HELP THE PIGMENTATION OF SKIN OR HAIR | LVMH RECHERCHE (FR) | 1991-06-13 | — | — | WO | claimed |
| EP-1904020-A2 | NEW SLIMMING COSMETIC COMPOSITIONS | Sederma S.A.S. (FR) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007010478-A2 | SLIMMING COSMETIC COMPOSITIONS | SEDERMA (FR) | 2007-01-25 | — | — | WO | disclosed |
| US-5470579-A | Xanthines, optionally incorporated in liposomes, for promoting skin or hair pigmentation | LVMH, RECHERCHE (FR) | 1995-11-28 | — | — | US | disclosed |
| EP-0502043-B1 | UTILIZATION OF XANTHINES, OPTIONALLY INCORPORATED IN LIPOSOMES IN ORDER TO HELP THE PIGMENTATION OF SKIN OR HAIR | LVMH RECH (FR) | 1995-03-01 | — | — | EP | disclosed |