SCHEMBL4622844

SCHEMBL4622844

CCCCCCCCCCCCc1cnn(-c2ccccc2)c1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.45
CNR2 P34972 1/20 0.45
LIPG Q9Y5X9 1/20 0.44
BID P55957 3/20 0.41
MCL1 Q07820 3/20 0.41
BCL2L1 Q07817 2/20 0.41
BAK1 Q16611 2/20 0.41
KAT8 Q9H7Z6 2/20 0.41
SAE1 Q9UBE0 2/20 0.41
NR4A3 Q92570 1/20 0.41
PPARG P37231 1/20 0.41
PPARA Q07869 1/20 0.41
EP300 Q09472 1/20 0.41
KAT2A Q92830 1/20 0.41
KAT2B Q92831 1/20 0.41
KAT5 Q92993 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
MAPT P10636 3/20 0.41
LMNA P02545 2/20 0.41
NPSR1 Q6W5P4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23398637 0.94 NR4A3 (0.43) CNR1CNR2NR4A3PPARGSMN1; SMN2
SCHEMBL23402338 0.88 USP2 (0.47) NR4A3PPARGMAPTLMNANPSR1
SCHEMBL23399486 0.81 NR4A3 (0.55) NR4A3PPARGSMN1; SMN2MAPTLMNA
SCHEMBL23398771 0.81 RAB9A (0.41) SMN1; SMN2MAPTLMNANPSR1RAB9A
SCHEMBL23403141 0.79 LMNA (0.46) SMN1; SMN2MAPTLMNANPSR1L3MBTL1
SCHEMBL27676109 0.76 RAB9A (0.49) SMN1; SMN2MAPTLMNANPSR1L3MBTL1
SCHEMBL23399778 0.75 HIF1A (0.41) SMN1; SMN2MAPTLMNAL3MBTL1KDM4E
SCHEMBL76980 0.75 NR4A3 (0.50) NR4A3SMN1; SMN2MAPTMAPK1ALDH1A1
SCHEMBL23399736 0.74 ALDH1A1 (0.42) SMN1; SMN2MAPTLMNAL3MBTL1KDM4E
SCHEMBL28080301 0.74 NR4A3 (0.49) NR4A3SMN1; SMN2MAPTMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1820054-B Polycondensates as dyeing promoters for hydrophobic polymer articles CIBA SC HOLDING AG 2012-11-14 CN disclosed
CN-102712785-A Polymers with low gel content and enhanced gas-fading CHEMTURA CORP 2012-10-03 CN disclosed
CN-1950436-B Flame retardants CIBA SC HOLDING AG 2012-09-05 CN disclosed
CN-102428139-A Scratch-resistant polypropylene BASF PERFORMANCE PRODUCTS LLC 2012-04-25 CN disclosed
CN-101454388-B N-substituted perfluoroalkylated pyrrolidines as surface modifiers CIBA HOLDING INC 2012-04-18 CN disclosed
CN-101273083-B Method for improving the flowability of polymer melts CIBA HOLDING INC 2012-04-18 CN disclosed
EP-1311635-B1 SOLVENT-BASED NON-FLUORESCENT INKS FOR WRITING INSTRUMENTS BASED UPON PIGMENT DISPERSIONS IN NON-AQUEOUS SOLVENTS BIC CORP (US) 2008-03-19 EP disclosed
CN-1969003-A Polystyrene-containing masterbatch composition for polyester modification CIBA SC HOLDING AG (CH) 2007-05-23 CN disclosed
EP-1311634-B1 SOLVENT-BASED FLUORESCENT INKS FOR WRITING INSTRUMENTS BASED UPON PIGMENT DISPERSIONS IN NON-AQUEOUS SOLVENTS BIC CORP (US) 2007-03-28 EP disclosed
CN-1263814-C Solvent-based fluorescent inks for writing instruments based upon pigment dispersions in non-aqueous solvents BIC CORP (US) 2006-07-12 CN disclosed
WO-2002016515-A1 SOLVENT-BASED FLUORESCENT INKS FOR WRITING INSTRUMENTS BASED UPON PIGMENT DISPERSIONS IN NON-AQUEOUS SOLVENTS BIC CORPORATION (US) 2002-02-28 WO disclosed
WO-2002016516-A1 SOLVENT-BASED NON-FLUORESCENT INKS FOR WRITING INSTRUMENTS BASED UPON PIGMENT DISPERSIONS IN NON-AQUEOUS SOLVENTS BIC CORPORATION (US) 2002-02-28 WO disclosed
CN-1274358-A Process for preparing phosphorus organic compounds CLARIANT FINANCE BVI LTD (VG) 2000-11-22 CN disclosed
EP-0936857-A2 ACTIVE-SUBSTANCE-CONTAINING MOULDED BODIES BASED ON BIODEGRADABLE THERMOPLASTICALLY PROCESSABLE POLYMERS BAYER AG (DE) 1999-08-25 EP disclosed
CN-1042546-C Cycloolefin polymer molding composition of improved stability to chemical degradation HOECHST AG (DE) 1999-03-17 CN disclosed
WO-1998019532-A2 ACTIVE-SUBSTANCE-CONTAINING MOULDED BODIES BASED ON BIODEGRADABLE THERMOPLASTICALLY PROCESSABLE POLYMERS BAYER AKTIENGESELLSCHAFT (DE) 1998-05-14 WO disclosed
CN-1143093-A Sulphur absorption speed reduced plastic HOECHST AG (DE) 1997-02-19 CN disclosed
CN-1130217-A Coloured fiber stabilized by anti-amine and ultraviolet absorption agent synergistic mixture CIBA GEIGY CO LTD (CH) 1996-09-04 CN disclosed
CN-1089280-A Improved the cycloolefin polymer molding composition of stability to chemical degradation HOECHST AG (DE) 1994-07-13 CN disclosed
EP-0468923-A2 Stabiliser compositions for polypropylene, comprising triazine compounds containing piperidine groups, and metal compounds CIBA-GEIGY AG (CH) 1992-01-29 EP disclosed