Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.40 |
| ▸ | LAP3 | P28838 | 1/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 5/20 | 0.36 |
| ▸ | CA2 | P00918 | 5/20 | 0.36 |
| ▸ | CA9 | Q16790 | 5/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28557843 | 1.00 | TP53 (0.47) | TP53ALDH1A1TDP1LMNAZDHHC7 | |
| Sulfuric Acid SCHEMBL28358739 | 0.89 | TP53 (0.59) | TP53ALDH1A1TDP1LMNALAP3 | |
| Sulfuric Acid SCHEMBL28354893 | 0.89 | TP53 (0.59) | TP53ALDH1A1TDP1LMNALAP3 | |
| Sulfuric Acid SCHEMBL28358738 | 0.89 | TP53 (0.59) | TP53ALDH1A1TDP1LMNALAP3 | |
| Sulfuric Acid SCHEMBL28354891 | 0.89 | TP53 (0.59) | TP53ALDH1A1TDP1LMNALAP3 | |
| Sulfuric Acid SCHEMBL29166569 | 0.87 | TP53 (0.57) | TP53ALDH1A1TDP1LMNALAP3 | |
| Sulfuric Acid SCHEMBL29166798 | 0.87 | TP53 (0.57) | TP53ALDH1A1TDP1LMNALAP3 | |
| SCHEMBL4330784 | 0.86 | ALDH1A1 (0.64) | TP53ALDH1A1TDP1LMNACA1 | |
| SCHEMBL29202942 | 0.81 | TP53 (0.55) | TP53ALDH1A1ZDHHC7LAP3SMPD1 | |
| SCHEMBL3137380 | 0.81 | TP53 (0.43) | TP53LMNAZDHHC7CA2GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970741-B1 | O/W/O TYPE MULTIPHASE EMULSION | SHISEIDO CO LTD (JP) | 2008-05-14 | — | — | EP | disclosed |
| EP-1604632-B1 | Cosmetic comprising a specific terpolymer | SHISEIDO CO LTD (JP) | 2007-06-06 | — | — | EP | disclosed |
| EP-1604632-A1 | Cosmetic comprising a specific terpolymer | Shiseido Co., Ltd. (JP) | 2005-12-14 | — | — | EP | disclosed |
| US-20050271611-A1 | Cosmetic | SHISEIDO CO., LTD. (JP) | 2005-12-08 | — | — | US | disclosed |
| US-6585986-B2 | Water swelling colloidal hydrated aluminum silicate clay with quaternary ammonium surfactant, and a fatty acid or higher alcohol; allows UV light protection powder to be blended in to skin without whiteness, emulsifier for sunscreen | SHISEIDO COMPANY, LTD. (JP) | 2003-07-01 | — | — | US | disclosed |
| US-20010044475-A1 | Gelling agent and gel compositions | SHISEIDO COMPANY, LTD. (JP) | 2001-11-22 | — | — | US | disclosed |
| US-6150425-A | COMPRISING AN OUTER PHASE OIL AND OIL IN WATER EMULSION IN THE INNER PHASE WHICH CONTAINING WATER, AN OIL BASED INGREDIENT, A SURFACTANT AND AN AMPHIPHILIC SUBSTANCE; PREPARED BY A HIGH PRESSURE OR ULTRASONIC EMULSIFICATION | SHISEIDO COMPANY, LTD. (JP) | 2000-11-21 | — | — | US | disclosed |
| EP-0970741-A1 | O/W/O TYPE MULTIPHASE EMULSION | SHISEIDO COMPANY LIMITED (JP) | 2000-01-12 | — | — | EP | disclosed |
| EP-0922740-A1 | GELLING AGENT AND GEL COMPOSITIONS | SHISEIDO COMPANY LIMITED (JP) | 1999-06-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050271611-A1 | Cosmetic | SQLE, CUTA, MITF | TP53 2715/4885ALDH1A1 940/4885TDP1 2491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.