Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | TSHR | P16473 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5144058 | 1.00 | ALDH1A1 (0.62) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL5145803 | 1.00 | ALDH1A1 (0.62) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL4630885 | 1.00 | ALDH1A1 (0.62) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL4698719 | 1.00 | ALDH1A1 (0.62) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL4630359 | 0.98 | TSHR (0.61) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL131719 | 0.94 | TSHR (0.60) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL130905 | 0.87 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL10445790 | 0.85 | TSHR (0.49) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL5147088 | 0.84 | TSHR (0.49) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL11416341 | 0.84 | TSHR (0.49) | ALDH1A1TSHRLMNACYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904500-A1 | NEW DERIVATIVES OF HEPTAAZAPHENALENE, METHODS FOR OBTAINING THEM, AND THEIR USE AS PROTECTING AGENTS AGAINST UV RADIATION | ISDIN, S.A. (ES) | 2008-04-02 | — | — | EP | claimed |
| WO-2007006807-A1 | NEW DERIVATIVES OF HEPTAAZAPHENALENE, METHODS FOR OBTAINING THEM, AND THEIR USE AS PROTECTING AGENTS AGAINST UV RADIATION | ISDIN, S.A. (ES) | 2007-01-18 | — | — | WO | claimed |