Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 7/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL462319 | 1.00 | S1PR5 (0.44) | S1PR5S1PR1RORCALDH1A1CHRM4 | |
| SCHEMBL463264 | 0.88 | USP30 (0.51) | S1PR5ALDH1A1CHRM4USP30 | |
| SCHEMBL463263 | 0.88 | USP30 (0.51) | S1PR5ALDH1A1CHRM4USP30 | |
| SCHEMBL1895760 | 0.80 | CCR5 (0.57) | S1PR5S1PR1RORCALDH1A1CCR5 | |
| SCHEMBL1894610 | 0.78 | RORC (0.60) | S1PR5S1PR1RORCALDH1A1MC4R | |
| SCHEMBL9925995 | 0.78 | RORC (0.60) | S1PR5S1PR1RORCALDH1A1MC4R | |
| SCHEMBL463216 | 0.78 | KMT2A (0.46) | CHRM4 | |
| SCHEMBL461319 | 0.78 | KMT2A (0.46) | CHRM4 | |
| SCHEMBL731368 | 0.76 | ALDH1A1 (0.47) | S1PR5S1PR1RORCALDH1A1MC4R | |
| SCHEMBL12303485 | 0.76 | RORC (0.64) | S1PR5S1PR1RORCCCR5FUCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |