SCHEMBL4623202

SCHEMBL4623202

Cc1noc(=O)c2ccc(NC(=O)C(=O)CC(C)(C)c3cccc4c3OCO4)cc12

nearest known ligand 0.55

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 20/20 0.55
PGR P06401 7/20 0.55
NR3C2 P08235 5/20 0.55
AR P10275 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14641397 0.86 NR3C1 (0.55) NR3C1PGRNR3C2AR
SCHEMBL4621610 0.86 NR3C1 (0.73) NR3C1PGRNR3C2AR
SCHEMBL5645477 0.84 NR3C1 (0.51) NR3C1PGRNR3C2AR
SCHEMBL6076827 0.83 NR3C1 (0.78) NR3C1PGRNR3C2AR
SCHEMBL4620586 0.82 NR3C1 (0.51) NR3C1PGRNR3C2AR
SCHEMBL5642843 0.80 NR3C1 (0.48) NR3C1PGRNR3C2AR
SCHEMBL4002508 0.80 NR3C1 (0.65) NR3C1PGRNR3C2AR
SCHEMBL5643383 0.79 NR3C1 (0.53) NR3C1PGRNR3C2AR
SCHEMBL14604850 0.79 NR3C1 (0.55) NR3C1PGRNR3C2AR
SCHEMBL4278672 0.79 NR3C1 (0.52) NR3C1PGRNR3C2AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1902049-A2 NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS Bayer Schering Pharma Aktiengesellschaft (DE) 2008-03-26 EP disclosed
US-20070010514-A1 Non-steroidal progesterone receptor modulators BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2007-01-11 US disclosed
US-20070010514-A1 Non-steroidal progesterone receptor modulators BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2007-01-11 US disclosed
US-20070010514-A1 Non-steroidal progesterone receptor modulators BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2007-01-11 US disclosed
WO-2006136461-A2 NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2006-12-28 WO disclosed
US-7112584-B2 Nonsteroidal antiinflammatory agents SCHERING AG (DE) 2006-09-26 US disclosed
EP-1572671-A1 NON-STEROIDAL ANTI-INFLAMMATORY AGENTS Schering Aktiengesellschaft (DE) 2005-09-14 EP disclosed
US-20040209875-A1 Nonsteroidal antiinflammatory agents SCHERIN AKTIENGESELLSCHAFT (DE) 2004-10-21 US disclosed
WO-2004058733-A1 NON-STEROIDAL ANTI-INFLAMMATORY AGENTS SCHERING AKTIENGESELLSCHAFT (DE) 2004-07-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070010514-A1 Non-steroidal progesterone receptor modulators PGR, PGRMC1, CYP19A1 NR3C1 69/4885PGR 1/4885NR3C2 37/4885
US-20040209875-A1 Nonsteroidal antiinflammatory agents PTGS1, PTGER1, PTGES NR3C1 90/4885PGR 648/4885NR3C2 236/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.