SCHEMBL4623398

SCHEMBL4623398

C=CNc1nnnc(NC=C)c1NC=C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22705125 0.56 RAPGEF4 (0.52)
SCHEMBL21459249 0.56
SCHEMBL13084092 0.56 LMNA (0.31)
SCHEMBL9208039 0.55
SCHEMBL21230343 0.54
SCHEMBL20751679 0.51 CYP1A2 (0.38)
SCHEMBL31153234 0.49 ALDH1A1 (0.35)
SCHEMBL21306180 0.46
SCHEMBL17599028 0.41
SCHEMBL576753 0.41

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1258481-B1 Enaminotriazines as UV filters BASF SE (DE) 2008-06-18 EP claimed
US-7217820-B2 Cosmetic or pharmaceutical preparations which comprise enaminotriazines as light protection agents, and novel enaminotriazines BASF AKTIENGESELLSCHAFT (DE) 2007-05-15 US claimed
US-20050089487-A1 Cosmetic or pharmaceutical preparations which comprise enaminotriazines as light protection agents, and novel enaminotriazines HEIDENFELDER THOMAS (DE) 2005-04-28 US claimed
US-20030044363-A1 Cosmetic or pharmaceutical preparations which comprise enaminotriazines as light protection agents, and novel enaminotriazines BASF AKTIENGESELLSCHAFT (DE) 2003-03-06 US claimed
EP-1258481-A1 Enaminotriazines as UV filters BASF AKTIENGESELLSCHAFT (DE) 2002-11-20 EP claimed
EP-1258481-B1 Enaminotriazines as UV filters BASF SE (DE) 2008-06-18 EP disclosed
US-7217820-B2 Cosmetic or pharmaceutical preparations which comprise enaminotriazines as light protection agents, and novel enaminotriazines BASF AKTIENGESELLSCHAFT (DE) 2007-05-15 US disclosed
US-6887460-B2 Cosmetic or pharmaceutical preparations which comprise enaminotriazines as light protection agents, and novel enaminotriazines BASF AKTIENGESELLSCHAFT (DE) 2005-05-03 US disclosed
US-20050089487-A1 Cosmetic or pharmaceutical preparations which comprise enaminotriazines as light protection agents, and novel enaminotriazines HEIDENFELDER THOMAS (DE) 2005-04-28 US disclosed
US-20030044363-A1 Cosmetic or pharmaceutical preparations which comprise enaminotriazines as light protection agents, and novel enaminotriazines BASF AKTIENGESELLSCHAFT (DE) 2003-03-06 US disclosed
EP-1258481-A1 Enaminotriazines as UV filters BASF AKTIENGESELLSCHAFT (DE) 2002-11-20 EP disclosed