Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | FDPS | P14324 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11951555 | 0.84 | FDPS (0.50) | KDM4EPOLBTDP1FDPSSMN1; SMN2 | |
| SCHEMBL178554 | 0.84 | ACHE (0.60) | TDP1CA1CA2ACHESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3657271 | 0.82 | ACHE (0.58) | TDP1CA1CA2ACHESMN1; SMN2 | |
| SCHEMBL20201966 | 0.82 | CALM1 (0.37) | KDM4EPOLBCALM1GAAALDH1A1 | |
| SCHEMBL462345 | 0.81 | FDPS (0.55) | KDM4EPOLBTDP1FDPSSMN1; SMN2 | |
| SCHEMBL16955884 | 0.81 | FDPS (0.48) | KDM4EPOLBTDP1FDPSSMN1; SMN2 | |
| SCHEMBL12446451 | 0.79 | FDPS (0.46) | KDM4EPOLBTDP1FDPSSMN1; SMN2 | |
| SCHEMBL11951574 | 0.78 | PDE4A (0.44) | KDM4EPOLBTDP1FDPSSMN1; SMN2 | |
| SCHEMBL11951552 | 0.76 | KDM4E (0.50) | KDM4EPOLBTDP1FDPSSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7621625 | 0.75 | GAA (0.54) | KDM4EPOLBTDP1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582709-B1 | AZOLOPYRIDIN-3-ONE DERIVATIVES AS INHIBITORS OF LIPASES AND PHOSPHOLIPASES | SANOFI SA (FR) | 2018-01-24 | — | — | EP | disclosed |