SCHEMBL4623671

SCHEMBL4623671

On1nnc2c(-c3ccccc3)cccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.48
MAPK1 P28482 1/20 0.48
ATM Q13315 1/20 0.48
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
KCNN4 O15554 1/20 0.38
ABCG2 Q9UNQ0 1/20 0.37
ALDH1A1 P00352 2/20 0.36
HPGD P15428 1/20 0.36
BCL2L1 Q07817 1/20 0.36
HSD17B10 Q99714 1/20 0.36
BRD4 O60885 1/20 0.36
NR1I2 O75469 1/20 0.36
SMARCA2 P51531 1/20 0.36
SMARCA4 P51532 1/20 0.36
PBRM1 Q86U86 1/20 0.36
CNR2 P34972 2/20 0.35
CNR1 P21554 1/20 0.35
METAP2 P50579 1/20 0.35
MAPK14 Q16539 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzotriazole SCHEMBL7192841 0.85 POLB (0.43) POLBMAPK1ATMLMNAMAPT
SCHEMBL6847668 0.83 ALDH1A1 (0.38) POLBMAPK1ATMLMNAMAPT
SCHEMBL5140531 0.79 MAPK1 (0.42) POLBMAPK1ATMLMNAMAPT
SCHEMBL2050918 0.79 SLC9A1 (0.48) LMNAMAPTKCNN4ABCG2ALDH1A1
2,4-Dihydroxybenzophenone SCHEMBL10614007 0.78 KMT2A (0.54) POLBMAPK1LMNAMAPTALDH1A1
SCHEMBL378660 0.73 POLB (0.50) POLBMAPK1ATMLMNAMAPT
SCHEMBL3282850 0.72 GRM2 (0.50) POLBMAPK1ATMLMNAMAPT
Water SCHEMBL3673310 0.72 POLB (0.48) POLBMAPK1ATMLMNAMAPT
SCHEMBL2670682 0.72 POLB (0.48) POLBMAPK1ATMLMNAMAPT
SCHEMBL2113290 0.72 MAPK1 (0.48) POLBMAPK1ATMLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0002539-B1 SELF-EXTINGUISHING EXPANDABLE STYRENE POLYMERS AND THEIR USE TOWARDS THE MANUFACTURE OF FOAMS BASF Aktiengesellschaft (DE) 1981-07-22 EP claimed
US-4218511-A PARTICLES COATED WITH ORGANIC BROMINE COMPOUNDS AND STABILIZERS THEREFOR BASF AKTIENGESELLSCHAFT (DE) 1980-08-19 US claimed
EP-0002539-A2 Self-extinguishing expandable styrene polymers and their use towards the manufacture of foams BASF Aktiengesellschaft (DE) 1979-06-27 EP claimed
CN-107502623-B Nanodiamonds delivering VEGF-siRNA, their preparation, activity and use 首都医科大学 2021-06-08 CN disclosed
US-20080310171-A1 Optical sheet DAICEL CHEMICAL INDUSTRIES, LTD. 2008-12-18 US disclosed
US-6917396-B2 Light diffusion film, plane light source device and liquid crystal display apparatus for enhancing a constant luminance and diffusing a light DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2005-07-12 US disclosed
US-20030156238-A1 Light diffusion film, surface illuminant device and liquid crystal display device DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-08-21 US disclosed
EP-0004050-B2 FLAME-PROTECTED EXPANDABLE STYRENE POLYMERS USEFUL IN FOAM PREPARATION BASF Aktiengesellschaft (DE) 1986-09-10 EP disclosed
US-4373060-A ULTAVIOLET ABSORBER INCORPORATED IN POLYMER GENERAL ELECTRIC COMPANY (US) 1983-02-08 US disclosed
EP-0004050-B1 FLAME-PROTECTED EXPANDABLE STYRENE POLYMERS USEFUL IN FOAM PREPARATION BASF Aktiengesellschaft (DE) 1981-11-25 EP disclosed
EP-0002539-B1 SELF-EXTINGUISHING EXPANDABLE STYRENE POLYMERS AND THEIR USE TOWARDS THE MANUFACTURE OF FOAMS BASF Aktiengesellschaft (DE) 1981-07-22 EP disclosed
US-4272583-A Flameproofed expandable styrene polymers BASF AKTIENGESELLSCHAFT (US) 1981-06-09 US disclosed
US-4218511-A PARTICLES COATED WITH ORGANIC BROMINE COMPOUNDS AND STABILIZERS THEREFOR BASF AKTIENGESELLSCHAFT (DE) 1980-08-19 US disclosed
US-4218511-A PARTICLES COATED WITH ORGANIC BROMINE COMPOUNDS AND STABILIZERS THEREFOR BASF AKTIENGESELLSCHAFT (DE) 1980-08-19 US disclosed
EP-0004050-A1 Flame-protected expandable styrene polymers useful in foam preparation BASF Aktiengesellschaft (DE) 1979-09-19 EP disclosed
EP-0002539-A2 Self-extinguishing expandable styrene polymers and their use towards the manufacture of foams BASF Aktiengesellschaft (DE) 1979-06-27 EP disclosed
EP-0002539-A2 Self-extinguishing expandable styrene polymers and their use towards the manufacture of foams BASF Aktiengesellschaft (DE) 1979-06-27 EP disclosed