Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NSD2 | O96028 | 3/20 | 0.47 |
| ▸ | CCR8 | P51685 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4444970 | 0.92 | FABP4 (0.56) | FABP4ALDH1A1NSD2CCR8GAA | |
| SCHEMBL4443345 | 0.88 | CCR8 (0.48) | FABP4ALDH1A1NSD2CCR8MAPT | |
| SCHEMBL4444610 | 0.88 | FABP4 (0.51) | FABP4ALDH1A1NSD2CCR8EDNRA | |
| SCHEMBL4443167 | 0.84 | NSD2 (0.55) | FABP4ALDH1A1NSD2CCR8KDM4E | |
| SCHEMBL4453211 | 0.84 | NSD2 (0.52) | FABP4ALDH1A1NSD2CCR8POLB | |
| SCHEMBL4444987 | 0.84 | NSD2 (0.66) | FABP4ALDH1A1NSD2CCR8KDM4E | |
| SCHEMBL4453000 | 0.83 | NSD2 (0.53) | FABP4ALDH1A1NSD2CCR8EDNRA | |
| SCHEMBL4449055 | 0.83 | NSD2 (0.68) | FABP4NSD2 | |
| Hydrochloric Acid SCHEMBL4445423 | 0.82 | NSD2 (0.69) | FABP4NSD2 | |
| SCHEMBL4454907 | 0.82 | CCR8 (0.51) | FABP4NSD2CCR8POLBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1402890-B1 | SULFONAMIDE DERIVATIVES | INST MED MOLECULAR DESIGN INC (JP) | 2008-01-09 | — | — | EP | disclosed |
| EP-1402890-A1 | SULFONAMIDE DERIVATIVES | Institute of Medicinal Molecular Design, Inc. (JP) | 2004-03-31 | — | — | EP | disclosed |