Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 18/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4623910 | 0.82 | HTR6 (0.64) | HTR6PTGS1PTGS2MAPT | |
| SCHEMBL833490 | 0.79 | HTR6 (1.00) | HTR6 | |
| SCHEMBL12868529 | 0.70 | HTR6 (0.78) | HTR6 | |
| SCHEMBL835912 | 0.69 | HTR6 (1.00) | HTR6 | |
| SCHEMBL8036424 | 0.68 | HTR6 (0.68) | HTR6PTGS1PTGS2MAPT | |
| SCHEMBL12868160 | 0.67 | HTR6 (0.64) | HTR6PTGS1PTGS2MAPT | |
| SCHEMBL5325197 | 0.67 | HTR6 (0.52) | HTR6MAPT | |
| SCHEMBL5325199 | 0.66 | HTR6 (0.51) | HTR6MAPT | |
| SCHEMBL21114803 | 0.66 | HTR6 (0.63) | HTR6 | |
| SCHEMBL24219916 | 0.65 | PKM (0.50) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948166-A1 | CARBAZOLE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | Suven Life Sciences Limited (IN) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007046111-A1 | CARBAZOLE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-04-26 | — | — | WO | disclosed |