Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL837941 | 0.90 | MGAM (0.42) | MGAMGAASIMGAM2HCAR2 | |
| SCHEMBL11081199 | 0.82 | MGAM (0.37) | MGAMGAASIMGAM2HCAR2 | |
| SCHEMBL837942 | 0.78 | MAPT (0.37) | ALDH1A1 | |
| SCHEMBL9725740 | 0.78 | — | — | |
| SCHEMBL7060302 | 0.75 | MGAM (0.41) | MGAMGAASIMGAM2PKM | |
| SCHEMBL10983086 | 0.75 | MGAM (0.41) | MGAMGAASIMGAM2HCAR2 | |
| SCHEMBL5527208 | 0.75 | MGAM (0.41) | MGAMGAASIMGAM2PKM | |
| SCHEMBL3666311 | 0.75 | ADH1B (0.38) | ALDH1A1LMNA | |
| SCHEMBL3179660 | 0.74 | CES2 (0.43) | MEN1KMT2A | |
| SCHEMBL10913361 | 0.73 | MGAM (0.39) | MGAMGAASIMGAM2HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1067950-B1 | NEO-TRYPTOPHAN | MAYO FOUNDATION (US) | 2008-05-14 | — | — | EP | disclosed |
| US-5108990-A | GLUTAMIC ACID DERIVATIVES | ROUSSEL UCLAF (FR) | 1992-04-28 | — | — | US | disclosed |