Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | MLNR | O43193 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28458270 | 0.86 | ALDH1A1 (0.41) | KIF11CHRM2CHRM1CHRM3MLNR | |
| SCHEMBL9194628 | 0.84 | KCNN4 (0.40) | KIF11CHRM2CHRM1CHRM3KCNN4 | |
| SCHEMBL11782050 | 0.80 | KIF11 (0.48) | KIF11KCNH2KCNN4TAAR1CYP3A4 | |
| SCHEMBL28355635 | 0.80 | VDR (0.37) | KIF11CHRM2CHRM1CHRM3LMNA | |
| SCHEMBL7764290 | 0.79 | KCNN4 (0.43) | KIF11KCNN4LMNAMAPK1ALDH1A1 | |
| SCHEMBL29280866 | 0.79 | MAPK1 (0.48) | KIF11KCNN4LMNAMAPK1ALDH1A1 | |
| SCHEMBL27470644 | 0.79 | ALDH1A1 (0.43) | CHRM2CHRM1CHRM3MLNRHTR2A | |
| SCHEMBL11786350 | 0.77 | HTR1B (0.42) | KIF11HTR2AHRH1KCNN4LMNA | |
| SCHEMBL28081004 | 0.77 | KDM4E (0.42) | CHRM2CHRM1CHRM3OPRM1DRD3 | |
| SCHEMBL6421037 | 0.77 | KIF11 (0.43) | KIF11CHRM2CHRM1CHRM3MLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448571-B1 | HIGH REFRACTIVE INDEX AROMATIC-BASED SILOXANE MONOFUNCTIONAL MACROMONOMERS | BAUSCH & LOMB (US) | 2008-05-21 | — | — | EP | disclosed |
| US-7022749-B2 | High refractive index aromatic-based siloxane difunctional macromonomers | BAUSCH & LOMB INCORPORATED (US) | 2006-04-04 | — | — | US | disclosed |
| US-7009024-B2 | High refractive index aromatic-based siloxane difunctional macromonomers | BAUSCH & LOMB INCORPORATED (US) | 2006-03-07 | — | — | US | disclosed |
| US-7009023-B2 | Radiation transparent; lenses | BAUSCH & LOMB INCORPORATED (US) | 2006-03-07 | — | — | US | disclosed |
| US-7005494-B2 | High refractive index aromatic-based siloxane monofunctional macromonomers | BAUSCH & LOMB INCORPORATED (US) | 2006-02-28 | — | — | US | disclosed |
| US-6992162-B2 | High refractive index aromatic-based siloxane monofunctional macromonomers | BAUSCH & LOMB INCORPORATED (US) | 2006-01-31 | — | — | US | disclosed |
| US-6989430-B2 | High refractive index aromatic-based siloxane monofunctional macromonomers | BAUSCH & LOMB INCORPORATED (US) | 2006-01-24 | — | — | US | disclosed |
| US-6906162-B2 | High refractive index aromatic-based siloxane monofunctional macromonomers | BAUSCH & LOMB INCORPORATED (US) | 2005-06-14 | — | — | US | disclosed |
| US-20050085611-A1 | High refractive index aromatic-based siloxane difunctional macromonomers | BAUSCH & LOMB MEXICO, S.A. DE C.V. (MX) | 2005-04-21 | — | — | US | disclosed |
| US-6881808-B2 | High refractive index aromatic-based siloxane difunctional macromonomers | BAUSCH & LOMB INCORPORATED (US) | 2005-04-19 | — | — | US | disclosed |
| US-6730767-B2 | OPTICAL TRANSPARENT; BIOCOMPATIBLE MEDICAL EQUIPMENT | BAUSCH & LOMB INCORPORATED | 2004-05-04 | — | — | US | disclosed |
| US-6723816-B2 | OPTICS; RADIATION TRANSPARENT | BAUSCH & LOMB INCORPORATED | 2004-04-20 | — | — | US | disclosed |