Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.56 |
| ▸ | HTR2B | P41595 | 2/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | SELL | P14151 | 1/20 | 0.46 |
| ▸ | SELP | P16109 | 1/20 | 0.46 |
| ▸ | SELE | P16581 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7942520 | 0.81 | GABRA1 (0.61) | LMNATRPA1SLC6A2HTR2BCHRM1 | |
| SCHEMBL18357201 | 0.81 | ACHE (0.59) | LMNATRPA1SLC6A2HTR2BCHRM1 | |
| SCHEMBL1487428 | 0.79 | LMNA (0.54) | LMNATRPA1SLC6A2HTR2BCHRM1 | |
| SCHEMBL12023105 | 0.79 | MAPT (0.43) | LMNATRPA1SLC6A2HTR2BCHRM1 | |
| SCHEMBL544651 | 0.77 | CA1 (0.67) | LMNATRPA1SLC6A2HTR2BCHRM1 | |
| SCHEMBL2173349 | 0.76 | GABRA1 (0.68) | LMNATRPA1SLC6A2HTR2BCHRM1 | |
| SCHEMBL26769093 | 0.76 | SELL (0.65) | LMNATRPA1SLC6A2HTR2BCHRM1 | |
| SCHEMBL22430739 | 0.76 | LMNA (0.66) | LMNATRPA1SLC6A2HTR2BCHRM1 | |
| SCHEMBL11974268 | 0.74 | LMNA (0.48) | LMNATRPA1SLC6A2HTR2BCHRM1 | |
| SCHEMBL9857937 | 0.73 | FABP3 (0.55) | LMNATRPA1SLC6A2HTR2BCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448620-B1 | SUPPORTED BIS(PHOSPHORUS)LIGANDS AND THEIR USE IN THE CATALYSIS | INVISTA TECH SARL (CH) | 2008-06-04 | — | — | EP | disclosed |
| US-6984604-B2 | Supported bis(phosphorus) ligands and their use in the catalysis | INVISTA NORTH AMERICA S.A.R.L. (US) | 2006-01-10 | — | — | US | disclosed |
| EP-1448620-A1 | SUPPORTED BIS(PHOSPHORUS)LIGANDS AND THEIR USE IN THE CATALYSIS | E. I. du Pont de Nemours and Company (US) | 2004-08-25 | — | — | EP | disclosed |
| US-20030153691-A1 | Supported bis(phosphorus) ligands and their use in the catalysis | INVISTA NORTH AMERICA S.A.R.L. | 2003-08-14 | — | — | US | disclosed |
| WO-2003046019-A1 | SUPPORTED BIS(PHOSPHORUS)LIGANDS AND THEIR USE IN THE CATALYSIS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-06-05 | — | — | WO | disclosed |