SCHEMBL4624586

SCHEMBL4624586

COc1cccc(OC)c1C(=O)P(C(=O)c1c(OC)cccc1OC)c1ccc(OCC(C)C)cc1OCC(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.39
FOS P01100 1/20 0.39
JUN P05412 1/20 0.39
SIRT2 Q8IXJ6 1/20 0.38
MTNR1A P48039 3/20 0.38
MTNR1B P49286 3/20 0.38
XDH P47989 1/20 0.38
TRIM24 O15164 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
PDE4B Q07343 1/20 0.37
SLC16A3 O15427 2/20 0.37
SLC16A1 P53985 2/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37
CA14 Q9ULX7 1/20 0.37
GPR88 Q9GZN0 1/20 0.37
NR1H4 Q96RI1 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4629635 0.82 FOS (0.37) MAPTFOSJUNXDHTRIM24
SCHEMBL4623708 0.79 THRA (0.48) MAPT
SCHEMBL7187557 0.75 FOS (0.40) MAPTFOSJUNSIRT2MTNR1A
SCHEMBL4711652 0.75 MAPT (0.41) MAPTFOSJUNSIRT2MTNR1A
Lithium SCHEMBL7187564 0.75 MAPT (0.38) MAPTFOSJUNSIRT2MTNR1A
SCHEMBL4716254 0.73 MAPT (0.48) MAPTSMN1; SMN2CA12CA1CA2
SCHEMBL7189328 0.72 FOS (0.39) MAPTFOSJUNSIRT2MTNR1A
Lithium SCHEMBL7188985 0.72 SLC16A3 (0.36) MAPTFOSJUNSIRT2MTNR1A
SCHEMBL7188974 0.72 FOS (0.38) MAPTFOSJUNSIRT2MTNR1A
SCHEMBL4687529 0.71 PARP15 (0.59) SIRT2XDHSMN1; SMN2PARP15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1215044-B1 A laser engravable flexographic printing element and a method for forming a printing plate from the element DU PONT (US) 2008-05-21 EP claimed