SCHEMBL4711652

SCHEMBL4711652

COc1cccc(OC)c1C(=O)P(=O)(C(=O)c1c(OC)cccc1OC)c1ccc(OCC(C)C)cc1OCC(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
SLC16A3 O15427 3/20 0.38
SLC16A1 P53985 3/20 0.38
NR1H4 Q96RI1 2/20 0.38
FOS P01100 1/20 0.38
JUN P05412 1/20 0.38
SIRT2 Q8IXJ6 1/20 0.38
MTNR1A P48039 3/20 0.38
MTNR1B P49286 3/20 0.38
TP53 P04637 1/20 0.38
MCTS1 Q9ULC4 1/20 0.37
XDH P47989 1/20 0.37
TRIM24 O15164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4629642 0.82 FOS (0.36) MAPTSMN1; SMN2NR1H4FOSJUN
SCHEMBL29660692 0.82 FOS (0.36) MAPTSMN1; SMN2NR1H4FOSJUN
SCHEMBL5144192 0.81 THRB (0.47)
SCHEMBL7625324 0.81 MAPT (0.56) MAPTSMN1; SMN2CA12CA1CA2
SCHEMBL4710769 0.81 THRA (0.48)
SCHEMBL5043176 0.76 ITGB1 (0.43)
SCHEMBL4624586 0.75 MAPT (0.39) MAPTSMN1; SMN2CA12CA1CA2
Lithium SCHEMBL7187564 0.74 MAPT (0.38) MAPTSMN1; SMN2CA12CA1CA2
SCHEMBL7187557 0.74 FOS (0.40) MAPTSMN1; SMN2CA12CA1CA2
SCHEMBL4708242 0.74 MAPT (0.50) MAPTSMN1; SMN2CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1215044-B1 A laser engravable flexographic printing element and a method for forming a printing plate from the element DU PONT (US) 2008-05-21 EP claimed
US-6737216-B2 TO FORM A RELIEF SURFACE E.I. DU PONT DE NEMOURS AND COMPANY 2004-05-18 US claimed
US-20020123003-A1 To form a relief surface E.I. DU PONT DE NEMOURS AND COMPANY 2002-09-05 US claimed
EP-1215044-A2 A laser engravable flexographic printing element and a method for forming a printing plate from the element E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-06-19 EP claimed
EP-1215044-B1 A laser engravable flexographic printing element and a method for forming a printing plate from the element DU PONT (US) 2008-05-21 EP disclosed
US-20020123003-A1 To form a relief surface E.I. DU PONT DE NEMOURS AND COMPANY 2002-09-05 US disclosed
EP-1215044-A2 A laser engravable flexographic printing element and a method for forming a printing plate from the element E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-06-19 EP disclosed
US-5965776-A PHOTOINITIATORS FOR THE PHOTOPOLYMERIZATION OF ETHYLENICALLY UNSATURATED COMPOUNDS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-10-12 US disclosed
US-5767169-A STORAGE STABLE, NONHYDROLYZING CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-06-16 US disclosed