Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | COMT | P21964 | 8/20 | 0.51 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL31267529 | 0.83 | COMT (0.71) | ALDH1A1COMTFTOKDM4EMAPT | |
| SCHEMBL7156189 | 0.83 | COMT (0.71) | ALDH1A1COMTFTOKDM4EMAPT | |
| SCHEMBL10728571 | 0.83 | COMT (0.71) | ALDH1A1COMTFTOKDM4EMAPT | |
| SCHEMBL11129818 | 0.83 | COMT (0.71) | ALDH1A1COMTFTOKDM4EMAPT | |
| SCHEMBL1873348 | 0.83 | COMT (0.71) | ALDH1A1COMTFTOKDM4EMAPT | |
| SCHEMBL9511332 | 0.83 | FTO (0.77) | ALDH1A1COMTFTOKDM4EMAPT | |
| SCHEMBL7151881 | 0.83 | COMT (0.71) | ALDH1A1COMTFTOKDM4EMAPT | |
| SCHEMBL3271681 | 0.83 | COMT (0.71) | ALDH1A1COMTFTOKDM4EMAPT | |
| SCHEMBL31267557 | 0.83 | PSMD14 (0.51) | ALDH1A1CYP1A2ALOX15HIF1AHSD17B10 | |
| Actinoquinol SCHEMBL3037158 | 0.77 | ALDH1A1 (0.61) | ALDH1A1KDM4EGAAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412438-B1 | INK JET INK COMPOSITIONS CONTAINING FLUOROCHEMICAL SURFACTANTS | 3M INNOVATIVE PROPERTIES CO (US) | 2008-05-28 | — | — | EP | disclosed |