Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 7/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | STK17B | O94768 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14323699 | 0.89 | GAA (0.52) | NPC1SMN1; SMN2RAB9AGAAATM | |
| SCHEMBL4623926 | 0.78 | PDE4A (0.40) | NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL3699162 | 0.75 | GAA (0.53) | NPC1SMN1; SMN2RAB9AGAAALOX5 | |
| SCHEMBL14322565 | 0.72 | GAA (0.51) | NPC1SMN1; SMN2RAB9AGAAALOX5 | |
| SCHEMBL28638326 | 0.72 | PPARG (0.52) | ALOX5PTPN1PPARGPPARDCYP3A4 | |
| SCHEMBL10495514 | 0.72 | PPARG (0.59) | GAAALOX5PTPN1PPARGPPARD | |
| SCHEMBL29682746 | 0.72 | PPARG (0.59) | GAAALOX5PTPN1PPARGPPARD | |
| SCHEMBL31546026 | 0.70 | GAA (0.55) | NPC1SMN1; SMN2GAAKDM4ECYP3A4 | |
| SCHEMBL6450302 | 0.70 | ACMSD (0.51) | NPC1SMN1; SMN2RAB9AGAAALOX5 | |
| SCHEMBL14323092 | 0.69 | GAA (0.48) | NPC1SMN1; SMN2RAB9AGAAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0860455-B1 | Photocrosslinkable polymers | ROLIC AG (CH) | 2008-06-04 | — | — | EP | disclosed |
| US-6632909-B2 | Alkylenedi- acrylates and acrylamides containing phenyl groups substituted with at least two alkoxy or fluoroalkoxy groups; use in orientation layers for liquid crystals, and in optical components, in particular hybrid layer elements. | ROLIC AG (CH) | 2003-10-14 | — | — | US | disclosed |
| US-20020061996-A1 | Photocrosslinkable polymers | BUCHECKER RICHARD (CH) | 2002-05-23 | — | — | US | disclosed |
| EP-0860455-A2 | Photocrosslinkable polymers | Rolic AG (CH) | 1998-08-26 | — | — | EP | disclosed |