Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7068161 | 0.82 | RAB9A (0.43) | PDE4APDE4BPDE4CPDE4DTP53 | |
| SCHEMBL11247180 | 0.79 | PDE4A (0.51) | PDE4APDE4BPDE4CPDE4DC5AR1 | |
| SCHEMBL4624708 | 0.78 | NPC1 (0.43) | ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL9778645 | 0.76 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DC5AR1 | |
| SCHEMBL18124437 | 0.76 | OPRM1 (0.53) | TP53HIF1ANPC1RAB9ALMNA | |
| SCHEMBL9778943 | 0.74 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4DAPP | |
| SCHEMBL9778687 | 0.74 | APP (0.55) | PDE4APDE4BPDE4CPDE4DAPP | |
| SCHEMBL9778463 | 0.72 | PDE4A (0.55) | PDE4APDE4BPDE4CPDE4DAPP | |
| SCHEMBL9778720 | 0.72 | APP (0.53) | PDE4APDE4BPDE4CPDE4DAPP | |
| SCHEMBL15922822 | 0.72 | HTR1A (0.65) | HTR1AADRA1DADRA1AADRA1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0860455-B1 | Photocrosslinkable polymers | ROLIC AG (CH) | 2008-06-04 | — | — | EP | disclosed |
| US-6632909-B2 | Alkylenedi- acrylates and acrylamides containing phenyl groups substituted with at least two alkoxy or fluoroalkoxy groups; use in orientation layers for liquid crystals, and in optical components, in particular hybrid layer elements. | ROLIC AG (CH) | 2003-10-14 | — | — | US | disclosed |
| US-20020061996-A1 | Photocrosslinkable polymers | BUCHECKER RICHARD (CH) | 2002-05-23 | — | — | US | disclosed |
| EP-0860455-A2 | Photocrosslinkable polymers | Rolic AG (CH) | 1998-08-26 | — | — | EP | disclosed |