SCHEMBL3699162

SCHEMBL3699162

CCOc1cc(C2OCCO2)ccc1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 8/20 0.53
ALDH1A1 P00352 6/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
MAPT P10636 2/20 0.48
AR P10275 1/20 0.48
THRB P10828 1/20 0.48
GPR55 Q9Y2T6 1/20 0.48
HPGD P15428 3/20 0.48
ALOX15 P16050 1/20 0.48
HSD17B10 Q99714 1/20 0.48
APOBEC3G Q9HC16 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.47
KDM4E B2RXH2 3/20 0.44
SIRT1 Q96EB6 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
ATM Q13315 1/20 0.44
ALOX5 P09917 1/20 0.44
PTPN1 P18031 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14322565 0.94 GAA (0.51) GAAALDH1A1MEN1KMT2AMAPT
SCHEMBL31546026 0.85 GAA (0.55) GAAALDH1A1MEN1KMT2AMAPT
SCHEMBL14323699 0.85 GAA (0.52) GAAALDH1A1MEN1KMT2AMAPT
SCHEMBL14323026 0.85 GAA (0.46) GAAALDH1A1MEN1KMT2AMAPT
SCHEMBL11913917 0.85 GAA (0.46) GAAALDH1A1MEN1KMT2AMAPT
SCHEMBL14323092 0.84 GAA (0.48) GAAALDH1A1MEN1KMT2AMAPT
SCHEMBL14330212 0.84 GAA (0.48) GAAALDH1A1MEN1KMT2AMAPT
SCHEMBL3690573 0.82 PPARG (0.64) GAAALDH1A1MEN1KMT2AALOX5
SCHEMBL367278 0.81 GAA (0.48) GAAALDH1A1MEN1KMT2AMAPT
SCHEMBL14322279 0.81 GAA (0.48) GAAALDH1A1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180037843-A1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2018-02-08 US claimed
EP-2723841-B1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2017-01-04 EP claimed
US-20160186093-A1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2016-06-30 US claimed
US-9309487-B2 Perfume systems THE PROCTER & GAMBLE COMPANY (US) 2016-04-12 US claimed
US-20140378360-A1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2014-12-25 US claimed
EP-2723841-A1 PERFUME SYSTEMS The Procter and Gamble Company (US) 2014-04-30 EP claimed
US-20120329696-A1 PERFUME SYSTEMS PROCTER & GAMBLE COMPANY, THE 2012-12-27 US claimed
WO-2012177357-A1 PERFUME SYSTEMS THE PROCTER & GAMBLE COMPANY (US) 2012-12-27 WO claimed
CN-119286137-A Method for preparing novel bumper material by using waste polyolefin plastics 湖南众科新材料有限公司 2025-01-10 CN disclosed
US-20180037843-A1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2018-02-08 US disclosed
US-20180037843-A1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2018-02-08 US disclosed
US-20180037843-A1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2018-02-08 US disclosed
US-9822327-B2 Perfume systems THE PROCTER & GAMBLE COMPANY (US) 2017-11-21 US disclosed
US-9822327-B2 Perfume systems THE PROCTER & GAMBLE COMPANY (US) 2017-11-21 US disclosed
US-20080269296-A1 DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONISTS BLANCO-PILLADO MARIA-JESUS 2008-10-30 US disclosed
US-20080255152-A1 DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY 2008-10-16 US disclosed
US-7381719-B2 Diaryl ethers as opioid receptor antagonist ELI LILLY AND COMPANY (US) 2008-06-03 US disclosed
EP-1562595-B1 DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONISTS LILLY CO ELI (US) 2008-05-21 EP disclosed
CN-1305852-C Diaryl ethers as opioid receptor antagonists LILLY CO ELI (US) 2007-03-21 CN disclosed
US-20060217372-A1 Diaryl ethers as opioid receptor antagonist ELI LILLY AND COMPANY 2006-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080269296-A1 DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONISTS OPRM1, OPRD1, OPRL1 GAA 3191/4885ALDH1A1 2083/4885MEN1 4617/4885
US-20180037843-A1 PERFUME SYSTEMS TRPA1, PORCN, PLIN5 GAA 2528/4885ALDH1A1 1292/4885MEN1 3884/4885
US-20080255152-A1 DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONISTS OPRM1, OPRD1, OPRL1 GAA 3189/4885ALDH1A1 2104/4885MEN1 4619/4885
US-20060217372-A1 Diaryl ethers as opioid receptor antagonist OPRM1, OPRL1, OPRD1 GAA 3406/4885ALDH1A1 2133/4885MEN1 4627/4885
US-20120329696-A1 PERFUME SYSTEMS TRPA1, PORCN, PLIN5 GAA 2528/4885ALDH1A1 1292/4885MEN1 3884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.