Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL46075 | 0.94 | L3MBTL1 (0.33) | ALDH1A1L3MBTL1POLBRECQLTSHR | |
| SCHEMBL45928 | 0.94 | POLB (0.33) | ALDH1A1L3MBTL1POLBRECQLMAPT | |
| SCHEMBL46169 | 0.89 | TSHR (0.33) | ALDH1A1L3MBTL1POLBMAPTTSHR | |
| SCHEMBL46267 | 0.88 | TSHR (0.36) | ALDH1A1L3MBTL1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL46065 | 0.88 | ALDH1A1 (0.34) | ALDH1A1L3MBTL1POLBRECQLMAPT | |
| SCHEMBL46035 | 0.88 | ALDH1A1 (0.31) | ALDH1A1L3MBTL1POLB | |
| SCHEMBL12070203 | 0.88 | ALDH1A1 (0.32) | ALDH1A1L3MBTL1POLBRECQLMAPT | |
| SCHEMBL46057 | 0.86 | P2RY12 (0.32) | ALDH1A1L3MBTL1POLBTSHR | |
| SCHEMBL37251 | 0.86 | ALDH1A1 (0.32) | ALDH1A1L3MBTL1POLBRECQLMAPT | |
| SCHEMBL46079 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2575469-B1 | PESTICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-14 | — | — | EP | disclosed |
| EP-2575472-B1 | METHOD OF CONTROLLING NEONICOTINOID RESISTANT HEMIPTERA USING SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-07-19 | — | — | EP | disclosed |
| US-9485989-B2 | Method of controlling neonicotinoid resistant hemiptera | SYNGENTA PARTICIPATIONS AG (CH) | 2016-11-08 | — | — | US | disclosed |
| US-9485989-B2 | Method of controlling neonicotinoid resistant hemiptera | SYNGENTA PARTICIPATIONS AG (CH) | 2016-11-08 | — | — | US | disclosed |
| US-9462808-B2 | Pesticidal compositions | SYNGENTA PARTICIPANTS AG (CH) | 2016-10-11 | — | — | US | disclosed |
| US-9462808-B2 | Pesticidal compositions | SYNGENTA PARTICIPANTS AG (CH) | 2016-10-11 | — | — | US | disclosed |
| EP-2575449-B1 | PESTICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-04-27 | — | — | EP | disclosed |
| US-9018135-B2 | Pesticidal compositions | SYNGENTA PARTICIPATIONS AG (CH) | 2015-04-28 | — | — | US | disclosed |
| US-9018135-B2 | Pesticidal compositions | SYNGENTA PARTICIPATIONS AG (CH) | 2015-04-28 | — | — | US | disclosed |
| US-20140057930-A1 | METHOD OF CONTROLLING NEONICOTINOID RESISTANT HEMIPTERA | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-27 | — | — | US | disclosed |
| EP-2352376-B1 | SPIROHETEROCYCLIC N-OXYAMIDES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-01-01 | — | — | EP | disclosed |
| US-20130225411-A1 | PESTICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION LLC (US) | 2013-08-29 | — | — | US | disclosed |
| US-20130225411-A1 | PESTICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION LLC (US) | 2013-08-29 | — | — | US | disclosed |
| US-20130150394-A1 | PESTICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION LLC (US) | 2013-06-13 | — | — | US | disclosed |
| WO-2011151249-A2 | METHOD OF CONTROLLING NEONICOTINOID RESISTANT HEMIPTERA | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-08 | — | — | WO | disclosed |
| WO-2011151247-A2 | PESTICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-08 | — | — | WO | disclosed |
| WO-2011151248-A1 | PESTICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-08 | — | — | WO | disclosed |
| US-20110224079-A1 | SPIROHETEROCYCLIC N-OXYAMIDES AS PESTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2011-09-15 | — | — | US | disclosed |
| US-20110224079-A1 | SPIROHETEROCYCLIC N-OXYAMIDES AS PESTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2011-09-15 | — | — | US | disclosed |
| WO-2010063670-A1 | SPIROHETEROCYCLIC N-OXYAMIDES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150394-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, GAP43 | ALDH1A1 1634/4885L3MBTL1 366/4885POLB 4095/4885 |
| US-20130225411-A1 | PESTICIDAL COMPOSITIONS | DDT, CIP2A, CYP51A1 | ALDH1A1 4253/4885L3MBTL1 1693/4885POLB 2598/4885 |
| US-20140057930-A1 | METHOD OF CONTROLLING NEONICOTINOID RESISTANT HEMIPTERA | DDT, NAMPT, NISCH | ALDH1A1 1975/4885L3MBTL1 3845/4885POLB 2560/4885 |
| US-20110224079-A1 | SPIROHETEROCYCLIC N-OXYAMIDES AS PESTICIDES | DDT, ODC1, ACHE | ALDH1A1 227/4885L3MBTL1 2360/4885POLB 4547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.