Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 11/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470485 | 0.85 | GPR119 (0.43) | RETGPR119MCHR1 | |
| SCHEMBL470475 | 0.83 | GPR119 (0.38) | GPR119DPP4DPP8DPP9DPP7 | |
| SCHEMBL12064792 | 0.82 | GPR119 (0.45) | GPR119 | |
| SCHEMBL12064703 | 0.82 | MCHR1 (0.37) | RETGPR119MCHR1 | |
| SCHEMBL459423 | 0.81 | GPR119 (0.41) | RETGPR119MCHR1 | |
| SCHEMBL470590 | 0.81 | NTRK1 (0.38) | RETGPR119MCHR1 | |
| SCHEMBL470640 | 0.80 | MCHR1 (0.36) | RETGPR119MCHR1 | |
| SCHEMBL12064977 | 0.80 | GPR119 (0.38) | RETGPR119MCHR1 | |
| SCHEMBL12064704 | 0.80 | GPR119 (0.36) | RETGPR119MCHR1 | |
| SCHEMBL458011 | 0.79 | ACACB (0.35) | RETGPR119DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |